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Caroline Medioni

Explore the profile of Caroline Medioni including associated specialties, affiliations and a list of published articles. Areas
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Articles 12
Citations 383
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Recent Articles
1.
Medioni C, Vijayakumar J, Ephrussi A, Besse F
Methods Mol Biol . 2022 Apr; 2431:451-462. PMID: 35412292
Dynamic and local adjustments of the axonal proteome are observed in response to extracellular cues and achieved via translation of axonally localized mRNAs. To be localized, these mRNAs must be...
2.
Medioni C, Ephrussi A, Besse F
Methods Mol Biol . 2022 Jan; 2417:19-28. PMID: 35099788
Live-imaging of axonal cargoes within central nervous system has been a long-lasting interest for neurobiologists as axonal transport plays critical roles in neuronal growth, function, and survival. Many kinds of...
3.
Razetti A, Medioni C, Malandain G, Besse F, Descombes X
PLoS Comput Biol . 2018 Dec; 14(12):e1006627. PMID: 30507939
The confined and crowded environment of developing brains imposes spatial constraints on neuronal cells that have evolved individual and collective strategies to optimize their growth. These include organizing neurons into...
4.
Medioni C, Besse F
Methods Mol Biol . 2017 Nov; 1649:1-28. PMID: 29130187
The last past decade has witnessed a revolution in our appreciation of transcriptome complexity and regulation. This remarkable expansion in our knowledge largely originates from the advent of high-throughput methodologies,...
5.
Medioni C, Ephrussi A, Besse F
Nat Protoc . 2015 Mar; 10(4):574-84. PMID: 25763834
Axonal transport is essential for the initial growth, maintenance and synaptic plasticity of axons, and altered axonal transport has been observed in different models of neurodegenerative pathologies. Dissecting the mechanisms...
6.
Medioni C, Ramialison M, Ephrussi A, Besse F
Curr Biol . 2014 Mar; 24(7):793-800. PMID: 24656828
Neuronal remodeling is essential for the refinement of neuronal circuits in response to developmental cues [1-4]. Although this process involves pruning or retraction of axonal projections followed by axonal regrowth...
7.
Medioni C, Mowry K, Besse F
Development . 2012 Aug; 139(18):3263-76. PMID: 22912410
Intracellular targeting of mRNAs has long been recognized as a means to produce proteins locally, but has only recently emerged as a prevalent mechanism used by a wide variety of...
8.
Medioni C, Bertrand N, Mesbah K, Hudry B, Dupays L, Wolstein O, et al.
Dev Dyn . 2010 Oct; 239(12):3303-11. PMID: 20941780
Development of the mammalian heart is mediated by complex interactions between myocardial, endocardial, and neural crest-derived cells. Studies in Drosophila have shown that the Slit-Robo signaling pathway controls cardiac cell...
9.
Medioni C, Senatore S, Salmand P, Lalevee N, Perrin L, Semeriva M
Curr Opin Genet Dev . 2009 Sep; 19(5):518-25. PMID: 19717296
For the last 15 years the fly cardiovascular system has attracted developmental geneticists for its potential as a model system of organogenesis. Heart development in Drosophila indeed provides a remarkable...
10.
Medioni C, Astier M, Zmojdzian M, Jagla K, Semeriva M
J Cell Biol . 2008 Jul; 182(2):249-61. PMID: 18663140
Tubulogenesis is an essential component of organ development, yet the underlying cellular mechanisms are poorly understood. We analyze here the formation of the Drosophila melanogaster cardiac lumen that arises from...