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Carly C Neal

Explore the profile of Carly C Neal including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 927
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Recent Articles
1.
Zhou A, Marin N, Afrin S, Wong P, Tran J, Jacobs M, et al.
J Immunol . 2025 Mar; 214(1):1-11. PMID: 40073259
Natural killer (NK) cells are a promising approach for cellular cancer immunotherapy and are being investigated to treat patients with multiple myeloma (MM). We found that MM patient blood NK...
2.
Wong P, Leong J, Sohn H, Chang L, Keppel C, Neal C, et al.
Eur J Immunol . 2024 Sep; 54(12):e2451173. PMID: 39246120
Natural killer (NK) cells are innate lymphoid cells that protect a host from viral infections and malignancies. MicroRNA-146a (miR-146a) is an important regulator of immune function that is highly expressed...
3.
Wong P, Foltz J, Chang L, Neal C, Yao T, Cubitt C, et al.
J Clin Invest . 2023 Jun; 133(13). PMID: 37279078
Since the T-box transcription factors (TFs) T-BET and EOMES are necessary for initiation of NK cell development, their ongoing requirement for mature NK cell homeostasis, function, and molecular programming remains...
4.
Cubitt C, McClain E, Becker-Hapak M, Foltz J, Wong P, Wagner J, et al.
Mol Ther Oncolytics . 2022 Mar; 24:585-596. PMID: 35284622
Natural killer (NK) cells are cytotoxic innate lymphoid cells that are emerging as a cellular immunotherapy for various malignancies. NK cells are particularly dependent on interleukin (IL)-15 for their survival,...
5.
Berrien-Elliott M, Foltz J, Russler-Germain D, Neal C, Tran J, Gang M, et al.
Sci Transl Med . 2022 Feb; 14(633):eabm1375. PMID: 35196021
Natural killer (NK) cells are innate lymphoid cells that eliminate cancer cells, produce cytokines, and are being investigated as a nascent cellular immunotherapy. Impaired NK cell function, expansion, and persistence...
6.
Bednarski J, Zimmerman C, Berrien-Elliott M, Foltz J, Becker-Hapak M, Neal C, et al.
Blood . 2021 Dec; 139(11):1670-1683. PMID: 34871371
Pediatric and young adult (YA) patients with acute myeloid leukemia (AML) who relapse after allogeneic hematopoietic cell transplantation (HCT) have an extremely poor prognosis. Standard salvage chemotherapy and donor lymphocyte...
7.
Becker-Hapak M, Shrestha N, McClain E, Dee M, Chaturvedi P, Leclerc G, et al.
Cancer Immunol Res . 2021 Jul; 9(9):1071-1087. PMID: 34244297
Natural killer (NK) cells are a promising cellular therapy for cancer, with challenges in the field including persistence, functional activity, and tumor recognition. Briefly, priming blood NK cells with recombinant...
8.
Kerbauy L, Marin N, Kaplan M, Banerjee P, Berrien-Elliott M, Becker-Hapak M, et al.
Clin Cancer Res . 2021 May; 27(13):3744-3756. PMID: 33986022
Purpose: Natural killer (NK)-cell recognition and function against NK-resistant cancers remain substantial barriers to the broad application of NK-cell immunotherapy. Potential solutions include bispecific engagers that target NK-cell activity via...
9.
Berrien-Elliott M, Cashen A, Cubitt C, Neal C, Wong P, Wagner J, et al.
Cancer Discov . 2020 Aug; 10(12):1854-1871. PMID: 32826231
Natural killer (NK) cells are an emerging cancer cellular therapy and potent mediators of antitumor immunity. Cytokine-induced memory-like (ML) NK cellular therapy is safe and induces remissions in patients with...
10.
Gang M, Marin N, Wong P, Neal C, Marsala L, Foster M, et al.
Blood . 2020 Jul; 136(20):2308-2318. PMID: 32614951
Natural killer (NK) cells are a promising cellular immunotherapy for cancer. Cytokine-induced memory-like (ML) NK cells differentiate after activation with interleukin-12 (IL-12), IL-15, and IL-18, exhibit potent antitumor responses, and...