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Caitlin D Deane

Explore the profile of Caitlin D Deane including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 53
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Recent Articles
1.
Deane C, Fischer M, Shelat A
Nat Chem Biol . 2024 Apr; 20(7):807-809. PMID: 38609538
No abstract available.
2.
Deane C, Burkhart B, Saint-Vincent P, Tietz J, Lin A, Mitchell D
ACS Chem Biol . 2016 Jun; 11(8):2232-43. PMID: 27248686
Plantazolicin (PZN) is a ribosomally synthesized and post-translationally modified peptide (RiPP) natural product that exhibits extraordinarily narrow-spectrum antibacterial activity toward the causative agent of anthrax, Bacillus anthracis. During PZN biosynthesis,...
3.
Maxson T, Deane C, Molloy E, Cox C, Markley A, Lee S, et al.
ACS Chem Biol . 2015 Feb; 10(5):1217-26. PMID: 25668590
Streptolysin S (SLS) is a post-translationally modified peptide cytolysin that is produced by the human pathogen Streptococcus pyogenes. SLS belongs to a large family of azole-containing natural products that are...
4.
Deane C, Mitchell D
J Ind Microbiol Biotechnol . 2013 Oct; 41(2):315-31. PMID: 24142337
Natural product discovery is currently undergoing a transformation from a phenotype-driven field to a genotype-driven one. The increasing availability of genome sequences, coupled with improved techniques for identifying biosynthetic gene...
5.
Deane C, Melby J, Molohon K, Susarrey A, Mitchell D
ACS Chem Biol . 2013 Jul; 8(9):1998-2008. PMID: 23823732
Plantazolicin (PZN) is a polyheterocyclic natural product derived from a ribosomal peptide that harbors remarkable antibiotic selectivity for the causative agent of anthrax, Bacillus anthracis. To simultaneously establish the structure-activity...