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Tucker Maxson

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Articles 13
Citations 381
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Recent Articles
1.
Maxson T, Overholt W, Chivukula V, Caban-Figueroa V, Kongphet-Tran T, Medina Cordoba L, et al.
Microbiol Spectr . 2024 Apr; 12(6):e0418023. PMID: 38666793
The high-consequence pathogen causes human anthrax and often results in lethal infections without the rapid administration of effective antimicrobial treatment. Antimicrobial resistance profiling is therefore critical to inform post-exposure prophylaxis...
2.
Maxson T, Kongphet-Tran T, Mongkolrattanothai T, Travis T, Hendricks K, Parker C, et al.
Clin Infect Dis . 2022 Oct; 75(Suppl 3):S373-S378. PMID: 36251548
Bacillus anthracis, the causative agent of anthrax, is a high-consequence bacterial pathogen that occurs naturally in many parts of the world and is considered an agent of biowarfare or bioterrorism....
3.
Maxson T, Blancett C, Graham A, Stefan C, Minogue T
PLoS One . 2018 Dec; 13(12):e0209042. PMID: 30543695
Development and implementation of rapid antimicrobial susceptibility testing is critical for guiding patient care and improving clinical outcomes, especially in cases of sepsis. One approach to reduce the time-to-answer for...
4.
Maxson T, Taylor-Howell C, Minogue T
PLoS One . 2017 Sep; 12(8):e0183899. PMID: 28859120
Antibiotic resistant bacterial infections are a significant problem in the healthcare setting, in many cases requiring the rapid administration of appropriate and effective antibiotic therapy. Diagnostic assays capable of quickly...
5.
Tietz J, Schwalen C, Patel P, Maxson T, Blair P, Tai H, et al.
Nat Chem Biol . 2017 Mar; 13(5):470-478. PMID: 28244986
Ribosomally synthesized and post-translationally modified peptide (RiPP) natural products are attractive for genome-driven discovery and re-engineering, but limitations in bioinformatic methods and exponentially increasing genomic data make large-scale mining of...
6.
Maxson T, Tietz J, Hudson G, Guo X, Tai H, Mitchell D
J Am Chem Soc . 2016 Nov; 138(46):15157-15166. PMID: 27797509
Natural products (NPs) serve important roles as drug candidates and as tools for chemical biology. However, traditional NP discovery, largely based on bioassay-guided approaches, is biased toward abundant compounds and...
7.
Maxson T, Mitchell D
Tetrahedron . 2016 Jul; 72(25):3609-3624. PMID: 27429480
Antibiotics are a cornerstone of modern medicine and have significantly reduced the burden of infectious diseases. However, commonly used broad-spectrum antibiotics can cause major collateral damage to the human microbiome,...
8.
Molohon K, Saint-Vincent P, Park S, Doroghazi J, Maxson T, Hershfield J, et al.
ACS Infect Dis . 2016 May; 2(3):207-220. PMID: 27152321
Plantazolicin (PZN) is a ribosomally synthesized and post-translationally modified natural product from FZB42 and . Extensive tailoring to twelve of the fourteen amino acid residues in the mature natural product...
9.
Maxson T, Bertke J, Gray D, Mitchell D
Acta Crystallogr E Crystallogr Commun . 2015 Nov; 71(Pt 11):1401-7. PMID: 26594520
The crystal structure and absolute configuration of the two new title nelfinavir analogs, C24H35ClN4O5, (I), and C27H39ClN4O5, (II), have been determined. Each of these mol-ecules exhibits a number of disordered...
10.
Molloy E, Casjens S, Cox C, Maxson T, Ethridge N, Margos G, et al.
BMC Microbiol . 2015 Jul; 15:141. PMID: 26204951
Background: Streptolysin S (SLS) is a cytolytic virulence factor produced by the human pathogen Streptococcus pyogenes and other Streptococcus species. Related "SLS-like" toxins have been characterized in select strains of...