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C J March

Explore the profile of C J March including associated specialties, affiliations and a list of published articles. Areas
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Articles 56
Citations 4258
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Recent Articles
11.
Hoffman R, Castner B, Gerhart M, Gibson M, Rasmussen B, March C, et al.
Protein Sci . 1995 Mar; 4(3):382-6. PMID: 7795521
The mode of binding of interleukin-4 (IL-4) to its two known receptors, specific receptor IL-4R and a shared receptor gamma c, was investigated using gel filtration and gel electrophoresis. A...
12.
Sudarsanam S, March C, Srinivasan S
J Mol Biol . 1994 Aug; 241(2):143-9. PMID: 8057355
A method is presented for homology modeling of proteins bearing weak sequence identity to proteins of known tertiary structure. To accommodate non-identical amino acids in the core region, the backbone...
13.
Hoffman R, Schalk-Hihi C, Castner B, Gibson M, Rasmussen B, Zdanov A, et al.
FEBS Lett . 1994 Jun; 347(1):17-21. PMID: 8013654
A large number of cytokines have been shown to possess a four-helix bundle structure with a unique up-up-down-down connectivity. The receptors for this family of cytokines have been shown to...
14.
Srinivasan S, March C, Sudarsanam S
Biotechnology (N Y) . 1993 Dec; 11(13):1579-80. PMID: 7764249
No abstract available.
15.
Powers R, Garrett D, March C, Frieden E, Gronenborn A, Clore G
Biochemistry . 1993 Jul; 32(26):6744-62. PMID: 8329398
The high-resolution three-dimensional solution structure of recombinant human interleukin-4 (IL-4), a protein of approximately 15 kDa which plays a key role in the regulation of B and T lymphocytes, has...
16.
Fanslow W, Spriggs M, Rauch C, Clifford K, Macduff B, Ziegler S, et al.
Blood . 1993 Jun; 81(11):2998-3005. PMID: 8499634
Biotinylated interleukin-4 (IL-4) was used to examine IL-4 receptor (IL-4R) expression on a range of human B-cell lines by flow cytometry. Using high concentrations of biotinylated IL-4, we have identified...
17.
Srinivasan S, March C, Sudarsanam S
Protein Sci . 1993 Feb; 2(2):277-89. PMID: 8443604
We present an automated method incorporated into a software package, FOLDER, to fold a protein sequence on a given three-dimensional (3D) template. Starting with the sequence alignment of a family...
18.
Beckmann M, Gayle R, Cerretti D, March C, Srinivasan S, Sleath P
Adv Exp Med Biol . 1993 Jan; 351:155-69. PMID: 7942293
No abstract available.
19.
Kronheim S, Mumma A, Greenstreet T, Glackin P, van Ness K, March C, et al.
Arch Biochem Biophys . 1992 Aug; 296(2):698-703. PMID: 1321594
We have purified the IL-1 beta converting enzyme from the THP-1 cell line using standard chromatographic techniques and obtained the N-terminal amino acid sequence of this novel protein. After stimulation...
20.
Powers R, Garrett D, March C, Frieden E, Gronenborn A, Clore G
Science . 1992 Jun; 256(5064):1673-7. PMID: 1609277
The three-dimensional solution structure of recombinant human interleukin-4, a protein of 133 residues and 15.4 kilodaltons that plays a key role in the immune and inflammatory systems, has been solved...