C J Beckers
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Explore the profile of C J Beckers including associated specialties, affiliations and a list of published articles.
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25
Citations
1031
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Recent Articles
1.
Moudy R, Manning T, Beckers C
J Biol Chem
. 2001 Aug;
276(44):41492-501.
PMID: 11526113
The ability of intracellular parasites to monitor the viability of their host cells is essential for their survival. The protozoan parasite Toxoplasma gondii actively invades nucleated animal cells and replicates...
2.
Lebrun M, Fourmaux M, Mercereau-Puijalon O, Mann T, Beckers C, Samyn B, et al.
Cell Microbiol
. 2001 Feb;
2(4):353-64.
PMID: 11207591
Assay of the adhesion of cultured cells on Toxoplasma gondii tachyzoite protein Western blots identified a major adhesive protein, that migrated at 90 kDa in non-reducing gels. This band comigrated...
3.
Nakaar V, Beckers C, Polotsky V, Joiner K
Mol Biochem Parasitol
. 1999 Jan;
97(1-2):209-20.
PMID: 9879899
The Toxoplasma gondii nucleoside triphosphate hydrolase is the most active E-type ATPase yet identified, and was the first member of this new gene family to be cloned (Bermudes D, Peck...
4.
Karsten V, Qi H, Beckers C, Reddy A, Dubremetz J, Webster P, et al.
J Cell Biol
. 1998 Jun;
141(6):1323-33.
PMID: 9628889
All known proteins that accumulate in the vacuolar space surrounding the obligate intracellular protozoan parasite Toxoplasma gondii are derived from parasite dense granules. To determine if constitutive secretory vesicles could...
5.
Karsten V, Qi H, Beckers C, Joiner K
Methods
. 1998 Feb;
13(2):103-11.
PMID: 9405194
Little is known about the extent of conservation in the organization of the secretory pathway in organisms as different as prokaryotes, eukaryotes, and humans. The protozoan parasite Toxoplasma gondii allows...
6.
Beckers C, Wakefield T, Joiner K
Mol Biochem Parasitol
. 1997 Nov;
89(2):209-23.
PMID: 9364966
Genes for the Toxoplasma gondii dense granule and rhoptry proteins nucleoside triphosphate hydrolase 3 and ROP2 were expressed at high levels in the closely related parasite N. caninum. The protein...
7.
Joiner K, Bermudes D, Sinai A, Qi H, Polotsky V, Beckers C
Ann N Y Acad Sci
. 1996 Oct;
797:1-7.
PMID: 8993345
No abstract available.
8.
Beckers C, Roos D, Donald R, Luft B, Schwab J, Cao Y, et al.
J Clin Invest
. 1995 Jan;
95(1):367-76.
PMID: 7814637
We investigated potential targets for the activity of protein synthesis inhibitors against the protozoan parasite Toxoplasma gondii. Although nanomolar concentrations of azithromycin and clindamycin prevent replication of T. gondii in...
9.
Villanueva M, Beckers C, Pamer E
J Exp Med
. 1994 Dec;
180(6):2137-45.
PMID: 7964488
Listeria monocytogenes is a facultative intracellular bacterium that causes severe disease in neonates and immunocompromised adults. Although entry, multiplication, and locomotion of Listeria in the cytosol of infected cells are...
10.
Bermudes D, Peck K, Afifi M, Beckers C, Joiner K
J Biol Chem
. 1994 Nov;
269(46):29252-60.
PMID: 7961894
The obligate intracellular parasite Toxoplasma gondii produces a nucleoside triphosphate hydrolase (NTPase) (nucleoside-triphosphatase, EC 3.6.1.15) activable by dithiol-containing compounds. We have isolated the genomic DNA for the NTPase from the...