Byron C Knowles
Overview
Explore the profile of Byron C Knowles including associated specialties, affiliations and a list of published articles.
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Articles
10
Citations
224
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0
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Recent Articles
1.
Vandiver A, Thomas B, Karimzada M, Knowles B, Botten G, Spreafico R, et al.
Exp Dermatol
. 2021 May;
30(11):1711-1716.
PMID: 34036652
Background: Human papillomavirus (HPV) infection is known to promote the development of mucosal squamous cell carcinoma (mSCC), including pathologically high-grade lesions, but its role in cutaneous squamous cell carcinoma (cuSCC)...
2.
Vecerek N, Dupuy E, Kang Y, Sarantopoulos G, Worswick S, Knowles B
Dermatol Online J
. 2019 Aug;
25(7).
PMID: 31450283
We describe adult-onset Kawasaki disease (KD) and review clinical manifestations and treatment guidelines. Our patient is a 20-year-old female who initially presented to an outside hospital for fever, cervical lymphadenopathy,...
3.
Jeong H, Lim K, Kim K, Cho Y, Lee B, Knowles B, et al.
J Pathol
. 2019 May;
249(2):227-240.
PMID: 31144312
Rab25 can function as both a tumor suppressor and a tumor promoter across different tissues. This study sought to clarify the role of Rab25 as a tumor suppressor in skin...
4.
Schlegel C, Weis V, Knowles B, Lapierre L, Martin M, Dickman P, et al.
Dig Dis Sci
. 2017 Dec;
63(2):356-365.
PMID: 29218485
Objectives: Microvillus inclusion disease (MVID) is a severe form of neonatal diarrhea, caused mainly by mutations in MYO5B. Inactivating mutations in MYO5B causes depolarization of enterocytes in the small intestine,...
5.
Weis V, Knowles B, Choi E, Goldstein A, Williams J, Manning E, et al.
Cell Mol Gastroenterol Hepatol
. 2016 Mar;
2(2):131-157.
PMID: 27019864
Background And Aims: Inactivating mutations in MYO5B cause severe neonatal diarrhea in Microvillus Inclusion Disease. Loss of active MYO5B causes the formation of pathognomonic inclusions and aberrations in brush border...
6.
Knowles B, Weis V, Yu S, Roland J, Williams J, Alvarado G, et al.
J Cell Sci
. 2015 Feb;
128(8):1617-26.
PMID: 25673875
Rab11a is a key component of the apical recycling endosome that aids in the trafficking of proteins to the luminal surface in polarized epithelial cells. Utilizing conditional Rab11a-knockout specific to...
7.
Knowles B, Tyska M, Goldenring J
Gastroenterology
. 2014 Jun;
147(1):15-7.
PMID: 24954664
No abstract available.
8.
Knowles B, Roland J, Krishnan M, Tyska M, Lapierre L, Dickman P, et al.
J Clin Invest
. 2014 Jun;
124(7):2947-62.
PMID: 24892806
Microvillus inclusion disease (MVID) is a severe form of congenital diarrhea that arises from inactivating mutations in the gene encoding myosin Vb (MYO5B). We have examined the association of mutations...
9.
Krishnan M, Lapierre L, Knowles B, Goldenring J
Mol Biol Cell
. 2013 Jan;
24(6):818-31.
PMID: 23345591
Rab25 is a tumor suppressor for colon cancer in humans and mice. To identify elements of intestinal polarity regulated by Rab25, we developed Caco2-BBE cell lines stably expressing short hairpin...
10.
Lapierre L, Avant K, Caldwell C, Oztan A, Apodaca G, Knowles B, et al.
Mol Biol Cell
. 2012 May;
23(12):2302-18.
PMID: 22553350
The Rab11 effector Rab11-family interacting protein 2 (Rab11-FIP2) regulates transcytosis through its interactions with Rab11a and myosin Vb. Previous studies implicated Rab11-FIP2 in the establishment of polarity in Madin-Darby canine...