Joseph T Roland
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Explore the profile of Joseph T Roland including associated specialties, affiliations and a list of published articles.
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73
Citations
1541
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Recent Articles
1.
Momoh M, Adeniran F, Ramos C, DelGiorno K, Seno H, Roland J, et al.
Physiol Rep
. 2025 Mar;
13(5):e70264.
PMID: 40051209
Intestinal tuft cells have recently been the focus of many studies due to their function in chemosensation and type 2 immunity in human gastrointestinal diseases. This study investigated the impact...
2.
Li J, Jacobse J, Pilat J, Kaur H, Gu W, Kang S, et al.
Mucosal Immunol
. 2025 Feb;
PMID: 39988202
Interleukin-10 (IL-10) is an immunomodulatory cytokine critical for intestinal immune homeostasis. IL-10 is produced by various immune cells but IL-10 receptor signaling in intestinal CXCR1 mononuclear phagocytes is necessary to...
3.
Bao S, Guo J, Lee H, Deng R, Cui C, Remedios L, et al.
Proc IEEE Int Symp Biomed Imaging
. 2025 Jan;
2024.
PMID: 39867569
Multiplex immunofluorescence (MxIF) imaging is a critical tool in biomedical research, offering detailed insights into cell composition and spatial context. As an example, DAPI staining identifies cell nuclei, while CD20...
4.
Remedios L, Bao S, Remedios S, Lee H, Cai L, Li T, et al.
J Med Imaging (Bellingham)
. 2024 Nov;
11(6):067501.
PMID: 39507410
Purpose: Cells are building blocks for human physiology; consequently, understanding the way cells communicate, co-locate, and interrelate is essential to furthering our understanding of how the body functions in both...
5.
Kaur H, Heiser C, McKinley E, Ventura-Antunes L, Harris C, Roland J, et al.
Commun Biol
. 2024 Oct;
7(1):1295.
PMID: 39478141
Spatially resolved molecular assays provide high dimensional genetic, transcriptomic, proteomic, and epigenetic information in situ and at various resolutions. Pairing these data across modalities with histological features enables powerful studies...
6.
Momoh M, Rathan-Kumar S, Burman A, Brown M, Adeniran F, Ramos C, et al.
Am J Physiol Gastrointest Liver Physiol
. 2024 Oct;
327(6):G877-G899.
PMID: 39404772
Functional loss of the motor protein myosin Vb (MYO5B) induces various defects in intestinal epithelial function and causes a congenital diarrheal disorder, namely, microvillus inclusion disease (MVID). Utilizing the MVID...
7.
Detres Roman C, Erwin M, Rudloff M, Revetta F, Murray K, Favret N, et al.
J Immunother Cancer
. 2024 Oct;
12(10).
PMID: 39362791
Background: Immune checkpoint blockade (ICB) therapies are an important treatment for patients with advanced cancers; however, only a subset of patients with certain types of cancer achieve durable remission. Cancer...
8.
Carty J, Bessho R, Zuchowski Y, Trapani J, Davidoff O, Kobayashi H, et al.
JCI Insight
. 2024 Oct;
9(22).
PMID: 39361429
Urinary concentration is an energy-dependent process that minimizes body water loss by increasing aquaporin 2 (AQP2) expression in collecting duct (CD) principal cells. To investigate the role of mitochondrial (mt)...
9.
Momoh M, Adeniran F, Ramos C, DelGiorno K, Seno H, Roland J, et al.
bioRxiv
. 2024 Sep;
PMID: 39345424
Background & Aims: Intestinal tuft cells have recently been the interest of studies in several human gastrointestinal diseases. However, the impact of tuft cell deletion on intestinal physiological functions are...
10.
Bao S, Zhu S, Kolachala V, Remedios L, Hwang Y, Sun Y, et al.
Proc SPIE Int Soc Opt Eng
. 2024 Sep;
12933.
PMID: 39309687
Crohn's disease (CD) is a chronic and relapsing inflammatory condition that affects segments of the gastrointestinal tract. CD activity is determined by histological findings, particularly the density of neutrophils observed...