Bryce J W van Denderen
Overview
Explore the profile of Bryce J W van Denderen including associated specialties, affiliations and a list of published articles.
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18
Citations
1004
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Recent Articles
1.
Lo T, Wang Q, Nickson J, van Denderen B, Deveson Lucas D, Chai H, et al.
mSphere
. 2024 Feb;
9(3):e0069623.
PMID: 38376217
Fungal infections cause a large health burden but are treated by only a handful of antifungal drug classes. Chromatin factors have emerged as possible targets for new antifungals. These targets...
2.
Wong N, Pope B, Candiloro I, Korbie D, Trau M, Wong S, et al.
Gigascience
. 2015 Nov;
4:55.
PMID: 26613017
Background: DNA methylation is a complex epigenetic marker that can be analyzed using a wide variety of methods. Interpretation and visualization of DNA methylation data can mask complexity in terms...
3.
Hugo H, Pereira L, Suryadinata R, Drabsch Y, Gonda T, Gunasinghe N, et al.
Breast Cancer Res
. 2013 Nov;
15(6):R113.
PMID: 24283570
Introduction: Epithelial-to-mesenchymal transition (EMT) promotes cell migration and is important in metastasis. Cellular proliferation is often downregulated during EMT, and the reverse transition (MET) in metastases appears to be required...
4.
Fraser S, Choy S, Pastor-Soler N, Li H, Davies M, Cook N, et al.
Am J Physiol Renal Physiol
. 2013 Jun;
305(5):F679-90.
PMID: 23785098
Salt reabsorption is the major energy-requiring process in the kidney, and AMP-activated protein kinase (AMPK) is an important regulator of cellular metabolism. Mice with targeted deletion of the β1-subunit of...
5.
van Denderen B, Thompson E
Nature
. 2013 Jan;
493(7433):487-8.
PMID: 23344357
No abstract available.
6.
Davis F, Kenny P, Soo E, van Denderen B, Thompson E, Cabot P, et al.
PLoS One
. 2011 Aug;
6(8):e23464.
PMID: 21850275
Background: The microenvironment plays a pivotal role in tumor cell proliferation, survival and migration. Invasive cancer cells face a new set of environmental challenges as they breach the basement membrane...
7.
Steinberg G, ONeill H, Dzamko N, Galic S, Naim T, Koopman R, et al.
J Biol Chem
. 2010 Sep;
285(48):37198-209.
PMID: 20855892
AMP-activated protein kinase (AMPK) β subunits (β1 and β2) provide scaffolds for binding α and γ subunits and contain a carbohydrate-binding module important for regulating enzyme activity. We generated C57Bl/6...
8.
Dzamko N, van Denderen B, Hevener A, Jorgensen S, Honeyman J, Galic S, et al.
J Biol Chem
. 2009 Nov;
285(1):115-22.
PMID: 19892703
The AMP-activated protein kinase (AMPK) is an alphabetagamma heterotrimer that regulates appetite and fuel metabolism. We have generated AMPK beta1(-/-) mice on a C57Bl/6 background that are viable, fertile, survived...
9.
Scott J, Oakhill J, van Denderen B
Front Biosci (Landmark Ed)
. 2009 Mar;
14(2):596-610.
PMID: 19273088
The AMP-activated protein kinase (AMPK) is the critical component of a highly conserved signalling pathway found in all eukaryotes that plays a key role in regulating metabolic processes in response...
10.
Scott J, van Denderen B, Jorgensen S, Honeyman J, Steinberg G, Oakhill J, et al.
Chem Biol
. 2008 Nov;
15(11):1220-30.
PMID: 19022182
The AMP-activated protein kinase (AMPK) is an alphabetagamma heterotrimer that plays a pivotal role in regulating cellular and whole-body metabolism. Activation of AMPK reverses many of the metabolic defects associated...