Tristan J Iseli
Overview
Explore the profile of Tristan J Iseli including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
385
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Recent Articles
1.
Dong Z, Su L, Esmaili S, Iseli T, Ramezani-Moghadam M, Hu L, et al.
J Mol Med (Berl)
. 2015 Jul;
93(12):1327-39.
PMID: 26153548
Unlabelled: Adiponectin protects against liver fibrosis, but the mechanisms have not been fully elucidated. Here, we showed that adiponectin upregulated inducible nitric oxide synthase (iNOS) messenger RNA (mRNA) and protein...
2.
Ramezani-Moghadam M, Wang J, Ho V, Iseli T, Alzahrani B, Xu A, et al.
J Biol Chem
. 2015 Jan;
290(9):5533-42.
PMID: 25575598
Hepatic stellate cells (HSC) are central players in liver fibrosis that when activated, proliferate, migrate to sites of liver injury, and secrete extracellular matrix. Obesity, a known risk factor for...
3.
Alzahrani B, Iseli T, Hebbard L
Cancer Lett
. 2013 Sep;
345(2):223-9.
PMID: 24007864
Liver cancer is the fifth most common cancer worldwide and the third most common cause of cancer mortality. Hepatocellular carcinoma (HCC) accounts for around 90% of primary liver cancers. Chronic...
4.
Kim M, Lee K, Iseli T, Hoy A, George J, Grewal T, et al.
Liver Int
. 2013 Sep;
33(10):1583-93.
PMID: 23998390
Background & Aims: A key factor in the development of type 2 diabetes and non-alcoholic fatty liver disease (NAFLD) is hepatic steatosis. Incubation of human hepatic cells with free fatty...
5.
Iseli T, Turner N, Zeng X, Cooney G, Kraegen E, Yao S, et al.
PLoS One
. 2013 May;
8(4):e62309.
PMID: 23638033
We recently showed that bitter melon-derived triterpenoids (BMTs) activate AMPK and increase GLUT4 translocation to the plasma membrane in vitro, and improve glucose disposal in insulin resistant models in vivo....
6.
Zeng X, Wang Y, Cantley J, Iseli T, Molero J, Hegarty B, et al.
PLoS One
. 2012 Aug;
7(7):e42115.
PMID: 22860063
The present study investigated the chronic efficacy of oleanolic acid (OA), a triterpenoid selected from our recent screening, on hyperglycemia in type-2 diabetic mice. C57BL/6J mice were fed a high-fat...
7.
Ren L, Chan S, Zeng X, Laybutt D, Iseli T, Sun R, et al.
PLoS One
. 2012 Feb;
7(2):e30816.
PMID: 22355328
Mitochondrial dysfunction and endoplasmic reticulum (ER) stress have been implicated in hepatic steatosis and insulin resistance. The present study investigated their roles in the development of hepatic steatosis and insulin...
8.
Brandon A, Hoy A, Wright L, Turner N, Hegarty B, Iseli T, et al.
Arch Biochem Biophys
. 2011 Mar;
509(2):133-41.
PMID: 21420928
Glucose infusion into rats causes skeletal muscle insulin resistance that initially occurs without changes in insulin signaling. The aim of the current study was to prolong glucose infusion and evaluate...
9.
Lu Q, Iseli T, Yin F, Ma C, Liu B, Lou D, et al.
Indian J Pediatr
. 2010 Apr;
77(5):547-50.
PMID: 20358314
Objective: To evaluate the relationship between waist-to-height ratio (WHtR) and glucose and lipid metabolism in Han adolescents aged 13-15 years. Methods: A study was conducted on 1665 Han adolescents aged...
10.
Scott J, van Denderen B, Jorgensen S, Honeyman J, Steinberg G, Oakhill J, et al.
Chem Biol
. 2008 Nov;
15(11):1220-30.
PMID: 19022182
The AMP-activated protein kinase (AMPK) is an alphabetagamma heterotrimer that plays a pivotal role in regulating cellular and whole-body metabolism. Activation of AMPK reverses many of the metabolic defects associated...