Bryan Snow
Overview
Explore the profile of Bryan Snow including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
752
Followers
0
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Recent Articles
1.
Yu H, Worrall L, Berger T, Petric M, Lin B, Vuckovic M, et al.
J Immunol
. 2023 Jul;
211(6):981-993.
PMID: 37493438
Current vaccine efforts to combat SARS-CoV-2 are focused on the whole spike protein administered as mRNA, viral vector, or protein subunit. However, the SARS-CoV-2 receptor-binding domain (RBD) is the immunodominant...
2.
Kubli S, Bassi C, Roux C, Wakeham A, Gobl C, Zhou W, et al.
Proc Natl Acad Sci U S A
. 2019 Feb;
116(9):3604-3613.
PMID: 30733286
Cancer cells have higher reactive oxygen species (ROS) than normal cells, due to genetic and metabolic alterations. An emerging scenario is that cancer cells increase ROS to activate protumorigenic signaling...
3.
Brenner D, Brustle A, Lin G, Lang P, Duncan G, Knobbe-Thomsen C, et al.
Proc Natl Acad Sci U S A
. 2014 Jan;
111(3):1060-5.
PMID: 24398517
The ability to mount a strong immune response against pathogens is crucial for mammalian survival. However, excessive and uncontrolled immune reactions can lead to autoimmunity. Unraveling how the reactive versus...
4.
Gorrini C, Baniasadi P, Harris I, Silvester J, Inoue S, Snow B, et al.
J Exp Med
. 2013 Jul;
210(8):1529-44.
PMID: 23857982
Oxidative stress plays an important role in cancer development and treatment. Recent data implicate the tumor suppressor BRCA1 in regulating oxidative stress, but the molecular mechanism and the impact in...
5.
Inoue S, Hao Z, Elia A, Cescon D, Zhou L, Silvester J, et al.
Genes Dev
. 2013 May;
27(10):1101-14.
PMID: 23699408
Tumorigenesis results from dysregulation of oncogenes and tumor suppressors that influence cellular proliferation, differentiation, apoptosis, and/or senescence. Many gene products involved in these processes are substrates of the E3 ubiquitin...
6.
Sasaki M, Knobbe C, Itsumi M, Elia A, Harris I, Chio I, et al.
Genes Dev
. 2012 Aug;
26(18):2038-49.
PMID: 22925884
Isocitrate dehydrogenase-1 (IDH1) R132 mutations occur in glioma, but their physiological significance is unknown. Here we describe the generation and characterization of brain-specific Idh1 R132H conditional knock-in (KI) mice. Idh1...
7.
Kim R, Peters M, Jang Y, Shi W, Pintilie M, Fletcher G, et al.
Cancer Cell
. 2005 Mar;
7(3):263-73.
PMID: 15766664
The phosphatidylinositol 3' kinase (PI3'K) pathway, which regulates cell survival, is antagonized by the PTEN tumor suppressor. The regulation of PTEN is unclear. A genetic screen of Drosophila gain-of-function mutants...
8.
Peters M, DeLuca C, Hirao A, Stambolic V, Potter J, Zhou L, et al.
Proc Natl Acad Sci U S A
. 2002 Aug;
99(17):11305-10.
PMID: 12172011
The tumor suppressor function of p53 has been attributed to its ability to regulate apoptosis and the cell cycle. In mammals, DNA damage, aberrant growth signals, chemotherapeutic agents, and UV...