Bryan E Snow
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Explore the profile of Bryan E Snow including associated specialties, affiliations and a list of published articles.
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22
Citations
779
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Recent Articles
1.
Zheng C, Snow B, Elia A, Nechanitzky R, Dominguez-Brauer C, Liu S, et al.
Nat Cancer
. 2023 Aug;
4(10):1437-1454.
PMID: 37640929
Cholinergic nerves are involved in tumor progression and dissemination. In contrast to other visceral tissues, cholinergic innervation in the hepatic parenchyma is poorly detected. It remains unclear whether there is...
2.
Nechanitzky R, Nechanitzky D, Ramachandran P, Duncan G, Zheng C, Gobl C, et al.
Cell Death Differ
. 2022 Dec;
30(2):407-416.
PMID: 36528755
Experimental autoimmune encephalomyelitis (EAE) is a mouse model of multiple sclerosis (MS) in which Th17 cells have a crucial but unclear function. Here we show that choline acetyltransferase (ChAT), which...
3.
Lukhele S, Rabbo D, Guo M, Shen J, Elsaesser H, Quevedo R, et al.
Immunity
. 2022 Nov;
55(12):2369-2385.e10.
PMID: 36370712
Type I and II interferons (IFNs) stimulate pro-inflammatory programs that are critical for immune activation, but also induce immune-suppressive feedback circuits that impede control of cancer growth. Here, we sought...
4.
Gui J, Zahedi F, Ortiz A, Cho C, Katlinski K, Alicea-Torres K, et al.
Nat Cancer
. 2021 Jun;
1(6):603-619.
PMID: 34124690
Primary tumor-derived factors (TDFs) act upon normal cells to generate a pre-metastatic niche, which promotes colonization of target organs by disseminated malignant cells. Here we report that TDFs-induced activation of...
5.
Bassi C, Fortin J, Snow B, Wakeham A, Ho J, Haight J, et al.
Cell Death Differ
. 2021 Jun;
28(11):3036-3051.
PMID: 34059798
The tumor suppressor PTEN is disrupted in a large proportion of cancers, including in HER2-positive breast cancer, where its loss is associated with resistance to therapy. Upon genotoxic stress, ataxia...
6.
Fortin J, Bassi C, Ramachandran P, Li W, Tian R, Zarrabi I, et al.
J Clin Invest
. 2021 Jan;
131(5).
PMID: 33444287
In order to sustain proficient life-long hematopoiesis, hematopoietic stem cells (HSCs) must possess robust mechanisms to preserve their quiescence and genome integrity. DNA-damaging stress can perturb HSC homeostasis by affecting...
7.
Fortin J, Tian R, Zarrabi I, Hill G, Williams E, Sanchez-Duffhues G, et al.
Cancer Cell
. 2020 Mar;
37(3):308-323.e12.
PMID: 32142668
Diffuse intrinsic pontine gliomas (DIPGs) are aggressive pediatric brain tumors for which there is currently no effective treatment. Some of these tumors combine gain-of-function mutations in ACVR1, PIK3CA, and histone...
8.
Kubli S, Vornholz L, Duncan G, Zhou W, Ramachandran P, Fortin J, et al.
Nat Commun
. 2019 Sep;
10(1):4069.
PMID: 31481706
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
9.
Kubli S, Vornholz L, Duncan G, Zhou W, Ramachandran P, Fortin J, et al.
Nat Commun
. 2019 Jun;
10(1):2678.
PMID: 31213601
Myeloid cells contribute to tumor progression, but how the constellation of receptors they express regulates their functions within the tumor microenvironment (TME) is unclear. We demonstrate that Fcmr (Toso), the...
10.
Hao Z, Sheng Y, Duncan G, Li W, Dominguez C, Sylvester J, et al.
Nat Commun
. 2017 Jan;
8:14003.
PMID: 28084302
T-cell proliferation is regulated by ubiquitination but the underlying molecular mechanism remains obscure. Here we report that Lys-48-linked ubiquitination of the transcription factor KLF4 mediated by the E3 ligase Mule...