Bryan E Snow
Overview
Explore the profile of Bryan E Snow including associated specialties, affiliations and a list of published articles.
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22
Citations
779
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Recent Articles
11.
Lemonnier F, Cairns R, Inoue S, Li W, Dupuy A, Broutin S, et al.
Proc Natl Acad Sci U S A
. 2016 Dec;
113(52):15084-15089.
PMID: 27956631
Oncogenic isocitrate dehydrogenase (IDH)1 and IDH2 mutations at three hotspot arginine residues cause an enzymatic gain of function that leads to the production and accumulation of the metabolite 2-hydroxyglutarate (2HG),...
12.
Inoue S, Li W, Tseng A, Beerman I, Elia A, Bendall S, et al.
Cancer Cell
. 2016 Jul;
30(2):337-348.
PMID: 27424808
Mutations in the isocitrate dehydrogenase-1 gene (IDH1) are common drivers of acute myeloid leukemia (AML) but their mechanism is not fully understood. It is thought that IDH1 mutants act by...
13.
Hao Z, Cairns R, Inoue S, Li W, Sheng Y, Lemonnier F, et al.
Proc Natl Acad Sci U S A
. 2016 Jan;
113(5):1387-92.
PMID: 26787889
Gain-of-function mutations in isocitrate dehydrogenase 1 (IDH1) are key drivers of hematopoietic malignancies. Although these mutations are most commonly associated with myeloid diseases, they also occur in malignancies of the...
14.
Hirata M, Sasaki M, Cairns R, Inoue S, Puviindran V, Li W, et al.
Proc Natl Acad Sci U S A
. 2015 Mar;
112(9):2829-34.
PMID: 25730874
Enchondromas are benign cartilage tumors and precursors to malignant chondrosarcomas. Somatic mutations in the isocitrate dehydrogenase genes (IDH1 and IDH2) are present in the majority of these tumor types. How...
15.
Reynolds G, Gao Q, Miller D, Snow B, Harrington L, Murnane J
DNA Repair (Amst)
. 2011 Sep;
10(11):1164-73.
PMID: 21945094
Telomerase serves to maintain telomeric repeat sequences at the ends of chromosomes. However, telomerase can also add telomeric repeat sequences at DNA double-strand breaks (DSBs), a process called chromosome healing....
16.
Snow B, Mateyak M, Paderova J, Wakeham A, Iorio C, Zakian V, et al.
Mol Cell Biol
. 2006 Nov;
27(3):1017-26.
PMID: 17130244
Pif1 is a 5'-to-3' DNA helicase critical to DNA replication and telomere length maintenance in the budding yeast Saccharomyces cerevisiae. ScPif1 is a negative regulator of telomeric repeat synthesis by...
17.
Martin-McCaffrey L, Willard F, Oliveira-dos-Santos A, Natale D, Snow B, Kimple R, et al.
Dev Cell
. 2004 Nov;
7(5):763-9.
PMID: 15525537
Heterotrimeric G protein alpha subunits, RGS proteins, and GoLoco motif proteins have been recently implicated in the control of mitotic spindle dynamics in C. elegans and D. melanogaster. Here we...
18.
Liu Y, Snow B, Kickhoefer V, Erdmann N, Zhou W, Wakeham A, et al.
Mol Cell Biol
. 2004 Jun;
24(12):5314-23.
PMID: 15169895
Vault poly(ADP-ribose) polymerase (VPARP) was originally identified as a minor protein component of the vault ribonucleoprotein particle, which may be involved in molecular assembly or subcellular transport. In addition to...
19.
Snow B, Erdmann N, Cruickshank J, Goldman H, Gill R, Robinson M, et al.
Curr Biol
. 2003 Apr;
13(8):698-704.
PMID: 12699629
Eukaryotic telomerase contains a telomerase reverse transcriptase (TERT) and an RNA template component that are essential for telomerase catalytic activity and several other telomerase-associated factors of which only a few...
20.
Arboleda M, Lyons J, Kabbinavar F, Bray M, Snow B, Ayala R, et al.
Cancer Res
. 2003 Jan;
63(1):196-206.
PMID: 12517798
To determine how AKT2 might contribute to tumor cell progression, a full-length, wild-type, human AKT2/protein kinase B (PKB)beta cDNA was transfected into a panel of eight human breast and ovarian...