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Brian Thompson

Explore the profile of Brian Thompson including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 65
Citations 1704
Followers 0
Related Specialties
General Medicine
Science
Biology
Top 10 Co-Authors
Charles P Lin
Vasilis Vasiliou
David R Nielsen
David C Thompson
Emily A Davidson
Daniel W Nebert
Irene M Ghobrial
Antonio Sacco
Hai T Ngo
Ying Chen
Published In
Hum Genomics
Blood
PLoS One
Int J Exerc Sci
PM R
Affiliations
Soon will be listed here.
Recent Articles
1.
A 12-year Retrospective Cohort Study of Point-of-care Ultrasound and Aortic Dissection Risk Score in Type A Aortic Dissection
Aston D, Burgess T, Badach S, Paladugu K, Thompson B, Schoenfeld E, et al.
J Emerg Med . 2024 Jul; 67(3):e288-e297. PMID: 39025714
Background: Aortic dissection (AD) is a vascular emergency with time-dependent mortality. Point-of-care ultrasound (POCUS) and AD risk score (ADRS) have been proposed as diagnostic tools to risk stratify patients and...
2.
The Acute Impacts of Resistance Training Performed with and without Blood Flow Restriction on Lower Body Muscular Power
Faller J, Thompson B, Sotir S, Ives S
Int J Exerc Sci . 2024 Jan; 16(6):1320-1333. PMID: 38288383
The American College of Sports Medicine recommends resistance training using at least 70% one repetition maximum to improve muscular strength and hypertrophy; however, these intensities may not be safe for...
3.
An AI-powered patient triage platform for future viral outbreaks using COVID-19 as a disease model
Charkoftaki G, Aalizadeh R, Santos-Neto A, Tan W, Davidson E, Nikolopoulou V, et al.
Hum Genomics . 2023 Aug; 17(1):80. PMID: 37641126
Over the last century, outbreaks and pandemics have occurred with disturbing regularity, necessitating advance preparation and large-scale, coordinated response. Here, we developed a machine learning predictive model of disease severity...
4.
Two Listeria monocytogenes outbreaks in a cancer centre: onsite food premises and their potential health risk to patients
Hobbs J, Lee C, Thompson B, Andrew A, Navarro C, Dubey V, et al.
BMC Public Health . 2023 Jul; 23(1):1443. PMID: 37507665
Background: This report describes two L. monocytogenes outbreak investigations that occurred in March and September of 2018 and that linked illness to a food premises located in an Ontario cancer...
5.
A Population of Tumor-Infiltrating CD4+ T Cells Co-Expressing CD38 and CD39 Is Associated with Checkpoint Inhibitor Resistance
Mitra A, Thompson B, Strange A, Amato C, Vassallo M, Dolgalev I, et al.
Clin Cancer Res . 2023 Jul; 29(20):4242-4255. PMID: 37505479
Purpose: We previously showed that elevated frequencies of peripheral blood CD3+CD4+CD127-GARP-CD38+CD39+ T cells were associated with checkpoint immunotherapy resistance in patients with metastatic melanoma. In the present study, we sought...
6.
CD4 Phenotypes Are Associated with Reduced Expansion of Tumor-Infiltrating Lymphocytes in Melanoma Patients Treated with Adoptive Cell Therapy
Thompson B, Strange A, Amato C, Hester-McCullough J, Sarnaik A, Weber J, et al.
J Immunol . 2023 Jul; 211(5):735-742. PMID: 37466381
Tumor-infiltrating lymphocyte (TIL) adoptive cell therapy is effective in treating malignant melanoma, but its success relies on the adequate ex vivo expansion of TIL. To assess correlates of TIL expansion,...
7.
Endocrine pancreas-specific gene deletion causes a severe diabetes phenotype
Davidson E, Chen Y, Singh S, Orlicky D, Thompson B, Wang Y, et al.
bioRxiv . 2023 Jul; PMID: 37398356
Reduced glutathione (GSH) is an abundant antioxidant that regulates intracellular redox homeostasis by scavenging reactive oxygen species (ROS). Glutamate-cysteine ligase catalytic (GCLC) subunit is the rate-limiting step in GSH biosynthesis....
8.
Fluid Restriction Dehydration Increase Core Temperature During Endurance Exercise Compared to Exercise Induced Dehydration
Sansone J, Guyer M, Mullin E, Thompson B
Int J Exerc Sci . 2023 Mar; 15(2):166-176. PMID: 36895794
This study aimed to evaluate the difference in heart rate and core temperature during aerobic exercise between two forms of dehydration: exercise-induced (EI) and fluid restricted (FR). Twenty-two subjects (...
9.
PhenoComb: a discovery tool to assess complex phenotypes in high-dimensional single-cell datasets
Burke P, Strange A, Monk E, Thompson B, Amato C, Woods D
Bioinform Adv . 2023 Jan; 2(1):vbac052. PMID: 36699375
Motivation: High-dimensional cytometry assays can simultaneously measure dozens of markers, enabling the investigation of complex phenotypes. However, as manual gating relies on previous biological knowledge, few marker combinations are often...
10.
Implementation of an automated, user-centered point-of-care ultrasound workflow improves documentation and billing
Thompson B, Schoenfeld E, Westafer L, Visintainer P, Budhram G
Acad Emerg Med . 2023 Jan; 30(3):180-186. PMID: 36617844
Background: Point-of-care ultrasound (POCUS) is a central component of emergency medical care. However, clinicians often fail to adequately document their examinations, causing problems for downstream clinicians and quality assurance processes...