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Charles P Lin

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Articles 143
Citations 10067
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Recent Articles
1.
Wu Q, Zhang J, Kumar S, Shen S, Kincaid M, Johnson C, et al.
Nature . 2024 Mar; 627(8005):839-846. PMID: 38509363
The bone marrow adjusts blood cell production to meet physiological demands in response to insults. The spatial organization of normal and stress responses are unknown owing to the lack of...
2.
Conedera F, Kokona D, Zinkernagel M, Stein J, Lin C, Alt C, et al.
J Neuroinflammation . 2024 Mar; 21(1):68. PMID: 38500151
Background: Retinal degeneration results from disruptions in retinal homeostasis due to injury, disease, or aging and triggers peripheral leukocyte infiltration. Effective immune responses rely on coordinated actions of resident microglia...
3.
Bonora M, Morganti C, van Gastel N, Ito K, Calura E, Zanolla I, et al.
Cell Stem Cell . 2024 Mar; 31(3):359-377.e10. PMID: 38458178
Mitochondrial fatty acid oxidation (FAO) is essential for hematopoietic stem cell (HSC) self-renewal; however, the mechanism by which mitochondrial metabolism controls HSC fate remains unknown. Here, we show that within...
4.
Bagramyan A, Lin C
Sci Rep . 2023 Oct; 13(1):17881. PMID: 37857684
We present a miniature oblique back-illumination microscope (mOBM) for imaging the microcirculation of human oral mucosa, enabling real-time, label-free phase contrast imaging of individual leukocytes circulating in the bloodstream, as...
5.
Conedera F, Runnels J, Stein J, Alt C, Enzmann V, Lin C
J Neuroinflammation . 2023 Sep; 20(1):206. PMID: 37689689
Background: Retinal degeneration is a disease affecting the eye, which is an immune-privileged site because of its anatomical and physiological properties. Alterations in retinal homeostasis-because of injury, disease, or aging-initiate...
6.
Jimenez-Dinamarca I, Prado Y, Tapia P, Gatica S, Alt C, Lin C, et al.
Biol Res . 2023 May; 56(1):24. PMID: 37165417
No abstract available.
7.
Aldawood Z, Mancinelli L, Geng X, Yeh S, Di Carlo R, C Leite T, et al.
Proc Natl Acad Sci U S A . 2023 Apr; 120(16):e2120826120. PMID: 37040407
In newborn humans, and up to approximately 2 y of age, calvarial bone defects can naturally regenerate. This remarkable regeneration potential is also found in newborn mice and is absent...
8.
Shah V, Hou J, Vinarsky V, Xu J, Surve M, Lin C, et al.
Elife . 2023 Mar; 12. PMID: 36994985
The specific functional properties of a tissue are distributed amongst its component cell types. The various cells act coherently, as an ensemble, in order to execute a physiologic response. Modern...
9.
Jimenez-Dinamarca I, Prado Y, Tapia P, Gatica S, Alt C, Lin C, et al.
Biol Res . 2023 Mar; 56(1):8. PMID: 36869357
Background: Sepsis is an uncontrolled inflammatory response against a systemic infection that results in elevated mortality, mainly induced by bacterial products known as endotoxins, producing endotoxemia. Disseminated intravascular coagulation (DIC)...
10.
Haase C, Gustafsson K, Mei S, Yeh S, Richter D, Milosevic J, et al.
Nat Methods . 2022 Nov; 19(12):1622-1633. PMID: 36424441
Tissue function depends on cellular organization. While the properties of individual cells are increasingly being deciphered using powerful single-cell sequencing technologies, understanding their spatial organization and temporal evolution remains a...