David C Thompson
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Explore the profile of David C Thompson including associated specialties, affiliations and a list of published articles.
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120
Citations
2971
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Recent Articles
1.
Wang Y, Charkoftaki G, Orlicky D, Davidson E, Aalizadeh R, Sun N, et al.
Arch Toxicol
. 2024 Aug;
98(10):3241-3257.
PMID: 39192018
1,4-Dioxane (DX), an emerging water contaminant, is classified as a Group 2B liver carcinogen based on animal studies. Understanding of the mechanisms of action of DX liver carcinogenicity is important...
2.
Zuccaro P, Thompson D, de Boer J, Llompart M, Watterson A, Bilott R, et al.
Environ Sci Technol
. 2024 Feb;
58(6):2591-2594.
PMID: 38301275
No abstract available.
3.
Wang Y, Popovic Z, Charkoftaki G, Garcia-Milian R, Lam T, Thompson D, et al.
Chem Biol Interact
. 2023 Sep;
384:110714.
PMID: 37716420
Colon cancer is the third leading cause of cancer death globally. Although early screenings and advances in treatments have reduced mortality since 1970, identification of novel targets for therapeutic intervention...
4.
Charkoftaki G, Aalizadeh R, Santos-Neto A, Tan W, Davidson E, Nikolopoulou V, et al.
Hum Genomics
. 2023 Aug;
17(1):80.
PMID: 37641126
Over the last century, outbreaks and pandemics have occurred with disturbing regularity, necessitating advance preparation and large-scale, coordinated response. Here, we developed a machine learning predictive model of disease severity...
5.
Zuccaro P, Licato J, Davidson E, Thompson D, Vasiliou V
Case Stud Chem Environ Eng
. 2023 Aug;
7.
PMID: 37575658
Background: Despite widespread global use of artificial turf fields, there is a paucity of research assessing the presence of potentially harmful chemicals within the field components. Objective: This pilot study...
6.
Tehrani A, Anderson J, Chakraborty D, Rodriguez-Hernandez J, Thompson D, Verstraelen T, et al.
J Comput Chem
. 2023 Aug;
44(25):1998-2015.
PMID: 37526138
The numerical ill-conditioning associated with approximating an electron density with a convex sum of Gaussian or Slater-type functions is overcome by using the (extended) Kullback-Leibler divergence to measure the deviation...
7.
Wang Y, Charkoftaki G, Davidson E, Orlicky D, Tanguay R, Thompson D, et al.
Curr Opin Environ Sci Health
. 2023 Jul;
29.
PMID: 37483863
1,4-Dioxane (DX) is an emerging drinking water contaminant worldwide, which poses a threat to public health due to its demonstrated liver carcinogenicity and potential for human exposure. The lack of...
8.
Alzheimer's disease: using gene/protein network machine learning for molecule discovery in olive oil
Rita L, Neumann N, Laponogov I, Gonzalez G, Veselkov D, Pratico D, et al.
Hum Genomics
. 2023 Jul;
17(1):57.
PMID: 37420280
Alzheimer's disease (AD) poses a profound human, social, and economic burden. Previous studies suggest that extra virgin olive oil (EVOO) may be helpful in preventing cognitive decline. Here, we present...
9.
Davidson E, Chen Y, Singh S, Orlicky D, Thompson B, Wang Y, et al.
bioRxiv
. 2023 Jul;
PMID: 37398356
Reduced glutathione (GSH) is an abundant antioxidant that regulates intracellular redox homeostasis by scavenging reactive oxygen species (ROS). Glutamate-cysteine ligase catalytic (GCLC) subunit is the rate-limiting step in GSH biosynthesis....
10.
Thompson D, Copeland S
Drug Discov Today
. 2023 Jun;
28(8):103648.
PMID: 37263388
The concept of serendipity or accidental discovery is typically discussed in the context of organizational research and development (RnD) through narratives involving 'renegade iconoclasts' laboring at the periphery. Recently, robust...