Brian M Robbings
Overview
Explore the profile of Brian M Robbings including associated specialties, affiliations and a list of published articles.
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13
Citations
116
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Recent Articles
1.
Caruso S, Cui X, Robbings B, Heaps N, Demikrol A, Lopes da Costa B, et al.
J Clin Invest
. 2025 Feb;
PMID: 39932789
Neuroretinal degenerations including retinitis pigmentosa (RP) comprise a heterogeneous collection of pathogenic mutations that ultimately result in blindness. Despite recent advances in precision medicine, therapies for rarer mutations are hindered...
2.
Hass D, Pandey K, Robbings B, Lim R, Chao J, Hurley J
Adv Exp Med Biol
. 2025 Feb;
1468:333-337.
PMID: 39930218
THT is an additive for culture medium used to maintain retinal pigment epithelial (RPE) cells. The individual components of THT are taurine, hydrocortisone, and triiodothyronine. The effects of THT on...
3.
Hass D, Giering E, Han J, Bisbach C, Pandey K, Robbings B, et al.
bioRxiv
. 2025 Jan;
PMID: 39764005
Photoreceptors in the retina of a vertebrate's eye are supported by a tissue adjacent to the retina, the retinal pigment epithelium (RPE). The RPE delivers glucose to the outer retina,...
4.
Hass D, Pandey K, Engel A, Horton N, Haydinger C, Robbings B, et al.
J Biol Chem
. 2024 Sep;
300(10):107772.
PMID: 39276938
Lipid-rich deposits called drusen accumulate under the retinal pigment epithelium (RPE) in the eyes of patients with age-related macular degeneration and Sorsby's fundus dystrophy (SFD). Drusen may contribute to photoreceptor...
5.
Nolan N, Cui X, Robbings B, Demirkol A, Pandey K, Wu W, et al.
Cell Rep Med
. 2024 Mar;
5(4):101459.
PMID: 38518771
Retinitis pigmentosa (RP) is one of the most common forms of hereditary neurodegeneration. It is caused by one or more of at least 3,100 mutations in over 80 genes that...
6.
Hass D, Pandey K, Engel A, Horton N, Robbings B, Lim R, et al.
bioRxiv
. 2023 Nov;
PMID: 37986876
Purpose: In age-related macular degeneration (AMD) and Sorsby's fundus dystrophy (SFD), lipid-rich deposits known as drusen accumulate under the retinal pigment epithelium (RPE). Drusen may contribute to photoreceptor and RPE...
7.
Kamat V, Grumbine M, Bao K, Mokate K, Khalil G, Cook D, et al.
Cell Rep Methods
. 2023 Nov;
3(11):100642.
PMID: 37963464
To address the needs of the life sciences community and the pharmaceutical industry in pre-clinical drug development to both maintain and continuously assess tissue metabolism and function with simple and...
8.
Grumbine M, Kamat V, Bao K, Crupi T, Mokate K, Lim R, et al.
J Vis Exp
. 2023 Jul;
(197).
PMID: 37522735
Many in vitro models used to investigate tissue function and cell biology require a flow of media to provide adequate oxygenation and optimal cell conditions required for the maintenance of...
9.
Berkowitz B, Podolsky R, Childers K, Roberts R, Katz R, Waseem R, et al.
Invest Ophthalmol Vis Sci
. 2022 Dec;
63(13):22.
PMID: 36576748
Purpose: To test the hypothesis that rod energy biomarkers in light and dark are similar in mice without functional rod transducin (Gnat1rd17). Methods: Gnat1rd17 and wildtype (WT) mice were studied...
10.
Hass D, Bisbach C, Robbings B, Sadilek M, Sweet I, Hurley J
Cell Rep
. 2022 Jun;
39(10):110917.
PMID: 35675773
Fumarate can be a surrogate for O as a terminal electron acceptor in the electron transport chain. Reduction of fumarate produces succinate, which can be exported. It is debated whether...