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Martin Sadilek

Explore the profile of Martin Sadilek including associated specialties, affiliations and a list of published articles. Areas
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Articles 75
Citations 2073
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Recent Articles
1.
Hass D, Pandey K, Engel A, Horton N, Haydinger C, Robbings B, et al.
J Biol Chem . 2024 Sep; 300(10):107772. PMID: 39276938
Lipid-rich deposits called drusen accumulate under the retinal pigment epithelium (RPE) in the eyes of patients with age-related macular degeneration and Sorsby's fundus dystrophy (SFD). Drusen may contribute to photoreceptor...
2.
Zhang C, Zhou D, Wang M, Song Y, Zhang C, Zhang M, et al.
Nat Commun . 2024 Jul; 15(1):5969. PMID: 39013920
The proficiency of phyllosphere microbiomes in efficiently utilizing plant-provided nutrients is pivotal for their successful colonization of plants. The methylotrophic capabilities of Methylobacterium/Methylorubrum play a crucial role in this process....
3.
Hass D, Pandey K, Engel A, Horton N, Robbings B, Lim R, et al.
bioRxiv . 2023 Nov; PMID: 37986876
Purpose: In age-related macular degeneration (AMD) and Sorsby's fundus dystrophy (SFD), lipid-rich deposits known as drusen accumulate under the retinal pigment epithelium (RPE). Drusen may contribute to photoreceptor and RPE...
4.
Herbst Z, Hong X, Sadilek M, Fuller M, Gelb M
Mol Genet Metab . 2023 Oct; 140(3):107698. PMID: 37820575
Newborn screening (NBS) for the full set of mucopolysaccharidoses (MPSs) is now possible by either measuring all of the relevant enzymatic activities in dried blood spots (DBS) using tandem mass...
5.
Hass D, Bisbach C, Sadilek M, Sweet I, Hurley J
Adv Exp Med Biol . 2023 Jul; 1415:435-441. PMID: 37440069
Metabolism is adapted to meet energetic needs. Based on the amount of ATP required to maintain plasma membrane potential, photoreceptor energy demands must be high. The available evidence suggests that...
6.
Sadilek M, Volny M, Ryzhov V
Mass Spectrom Rev . 2022 Oct; 43(3):413-419. PMID: 36218262
No abstract available.
7.
Hass D, Bisbach C, Robbings B, Sadilek M, Sweet I, Hurley J
Cell Rep . 2022 Jun; 39(10):110917. PMID: 35675773
Fumarate can be a surrogate for O as a terminal electron acceptor in the electron transport chain. Reduction of fumarate produces succinate, which can be exported. It is debated whether...
8.
Tsantilas K, Cleghorn W, Bisbach C, Whitson J, Hass D, Robbings B, et al.
Invest Ophthalmol Vis Sci . 2021 Nov; 62(14):20. PMID: 34797906
Purpose: The purpose of this study was to present our hypothesis that aging alters metabolic function in ocular tissues. We tested the hypothesis by measuring metabolism in aged murine tissues...
9.
Leonen C, Shimada M, Weller C, Nakadai T, Hsu P, Tyson E, et al.
Elife . 2021 Nov; 10. PMID: 34747692
The post-translational modification of histones by the small ubiquitin-like modifier (SUMO) protein has been associated with gene regulation, centromeric localization, and double-strand break repair in eukaryotes. Although sumoylation of histone...
10.
Hong X, Daiker J, Sadilek M, Ruiz-Schultz N, Kumar A, Norcross S, et al.
Genet Med . 2020 Nov; 23(3):555-561. PMID: 33214709
Purpose: Metachromatic leukodystrophy (MLD) is a lysosomal storage disorder caused by the deficiency of arylsulfatase A (ARSA), which results in the accumulation of sulfatides. Newborn screening for MLD may be...