Brian H Johnston
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Explore the profile of Brian H Johnston including associated specialties, affiliations and a list of published articles.
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27
Citations
452
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Recent Articles
1.
Sumpio B, Dallas A, Berger A, Li Z, Wang E, Mezghani I, et al.
Adv Wound Care (New Rochelle)
. 2024 Jan;
13(9):435-445.
PMID: 38183631
Diabetes mellitus (DM) affects over 422 million people globally. Patients with DM are subject to a myriad of complications, of which diabetic foot ulcers (DFUs) are the most common with...
2.
Chhalliyil P, Ilves H, Kazakov S, Howard S, Johnston B, Fagan J
Foods
. 2022 Feb;
11(4).
PMID: 35206099
The stated objective of the paper was to provide regulatory laboratories and industry laboratories a complete, legally robust method for the quantitative detection of SU canola [...].
3.
Chhalliyil P, Ilves H, Kazakov S, Howard S, Johnston B, Fagan J
Foods
. 2020 Sep;
9(9).
PMID: 32906573
Discussion regarding the regulatory status of genome-edited crops has focused on precision of editing and on doubts regarding the feasibility of analytical monitoring compliant with existing GMO regulations. Effective detection...
4.
Barberan-Soler S, Vo J, Hogans R, Dallas A, Johnston B, Kazakov S
Genome Biol
. 2018 Sep;
19(1):105.
PMID: 30173660
The ability to accurately quantify all the microRNAs (miRNAs) in a sample is important for understanding miRNA biology and for development of new biomarkers and therapeutic targets. We develop a...
5.
Dallas A, Trotsyuk A, Ilves H, Bonham C, Rodrigues M, Engel K, et al.
Tissue Eng Part A
. 2018 Apr;
25(1-2):44-54.
PMID: 29644938
In diabetes-associated chronic wounds, the normal response to hypoxia is impaired and many cellular processes involved in wound healing are hindered. Central to the hypoxia response is hypoxia-inducible factor-1α (HIF-1α),...
6.
Dallas A, Ilves H, Ma H, Chin D, MacLachlan I, Klumpp K, et al.
J Virol
. 2014 Jan;
88(9):4647-56.
PMID: 24478422
Unlabelled: We have recently shown that a cocktail of two short synthetic hairpin RNAs (sshRNAs), targeting the internal ribosome entry site of hepatitis C virus (HCV) formulated with lipid nanoparticles,...
7.
Ma H, Dallas A, Ilves H, Shorenstein J, MacLachlan I, Klumpp K, et al.
Gastroenterology
. 2013 Oct;
146(1):63-6.e5.
PMID: 24076507
Short synthetic hairpin RNAs (sshRNAs) (SG220 and SG273) that target the internal ribosome entry site of the hepatitis C virus (HCV) were formulated into lipid nanoparticles and administered intravenously to...
8.
Dallas A, Ilves H, Shorenstein J, Judge A, Spitler R, Contag C, et al.
Mol Ther Nucleic Acids
. 2013 Sep;
2:e123.
PMID: 24045712
We previously identified short synthetic shRNAs (sshRNAs) that target a conserved hepatitis C virus (HCV) sequence within the internal ribosome entry site (IRES) of HCV and potently inhibit HCV IRES-linked...
9.
Dallas A, Johnston B
Methods Mol Biol
. 2012 Oct;
942:279-90.
PMID: 23027057
Synthetic shRNAs that are too short to be Dicer substrates (short shRNAs or sshRNAs) can be highly potent RNAi effectors when properly designed, with activities similar to or more potent...
10.
Dallas A, Ilves H, Ge Q, Kumar P, Shorenstein J, Kazakov S, et al.
Nucleic Acids Res
. 2012 Jul;
40(18):9255-71.
PMID: 22810205
Small hairpin RNAs (shRNAs) having duplex lengths of 25-29 bp are normally processed by Dicer into short interfering RNAs (siRNAs) before incorporation into the RNA-induced silencing complex (RISC). However, shRNAs...