Brian Baridon
Overview
Explore the profile of Brian Baridon including associated specialties, affiliations and a list of published articles.
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7
Citations
80
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0
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Recent Articles
1.
Handyside B, Zhang L, Yates B, Xie L, Ismail A, Murphy R, et al.
Hum Gene Ther
. 2023 Dec;
35(1-2):36-47.
PMID: 38126359
Adeno-associated virus (AAV) vectors are used to deliver therapeutic transgenes, but host immune responses may interfere with transduction and transgene expression. We evaluated prophylactic corticosteroid treatment on AAV5-mediated expression in...
2.
Magat J, Jones S, Baridon B, Agrawal V, Wong H, Giaramita A, et al.
J Biol Chem
. 2022 Oct;
298(12):102625.
PMID: 36306823
Mucopolysaccharidosis type IIIA (MPS IIIA) is a lysosomal storage disorder caused by N-sulfoglucosamine sulfohydrolase (SGSH) deficiency. SGSH removes the sulfate from N-sulfoglucosamine residues on the nonreducing end of heparan sulfate...
3.
Grover A, Crippen-Harmon D, Nave L, Vincelette J, Wait J, Melton A, et al.
Drug Deliv Transl Res
. 2020 Jan;
10(2):425-439.
PMID: 31942701
BMN 250 is being developed as enzyme replacement therapy for Sanfilippo type B, a primarily neurological rare disease, in which patients have deficient lysosomal alpha-N-acetylglucosaminidase (NAGLU) enzyme activity. BMN 250...
4.
Aoyagi-Scharber M, Crippen-Harmon D, Lawrence R, Vincelette J, Yogalingam G, Prill H, et al.
Mol Ther Methods Clin Dev
. 2017 Jul;
6:43-53.
PMID: 28664165
Sanfilippo syndrome type B (mucopolysaccharidosis IIIB), caused by inherited deficiency of α--acetylglucosaminidase (NAGLU), required for lysosomal degradation of heparan sulfate (HS), is a pediatric neurodegenerative disorder with no approved treatment....
5.
West D, Pasumarthi R, Baridon B, Djan E, Trainor A, Griffey S, et al.
Genome Res
. 2015 Jan;
25(4):598-607.
PMID: 25591789
Expression of the bacterial beta-galactosidase reporter gene (lacZ) in the vector used for the Knockout Mouse Project (KOMP) is driven by the endogenous promoter of the target gene. In tissues...
6.
Borowsky A, Bandhuvula P, Kumar A, Yoshinaga Y, Nefedov M, Fong L, et al.
J Lipid Res
. 2012 Jul;
53(9):1920-31.
PMID: 22781001
Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid involved in immunity, inflammation, angiogenesis, and cancer. S1P lyase (SPL) is the essential enzyme responsible for S1P degradation. SPL augments apoptosis and is down-regulated...
7.
Li M, Baridon B, Trainor A, Djan E, Koehne A, Griffey S, et al.
Reproduction
. 2012 Jan;
143(4):449-53.
PMID: 22274886
Apolipoprotein E (Apoe)-deficient knockout mice were used to test the hypothesis that mutant mice preserved as evaporatively dried (ED) spermatozoa, stored at -80 °C for 6 months, and then recovered...