Bradley I Coleman
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Explore the profile of Bradley I Coleman including associated specialties, affiliations and a list of published articles.
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19
Citations
601
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Recent Articles
1.
Tagoe D, Ribeiro E Silva A, Drozda A, Coppens I, Coleman B, Gubbels M
Sci Rep
. 2024 Sep;
14(1):21819.
PMID: 39294204
Toxoplasma gondii is a polarized cell concentrating several secretory organelles at the apical pole. The secretory micronemes come in two sub-populations differentiated by dependence on Rab5A/C in their biogenesis. Calcium-dependent...
2.
Boyd T, Besche H, Goldhammer R, Alblooshi A, Coleman B
BMC Med Educ
. 2022 Nov;
22(1):821.
PMID: 36447223
Background: Students with developed self-regulated learning (SRL) skills demonstrate an ability to set individualized educational goals, select optimal learning strategies for reaching these goals, and reflect on overall progress. The...
3.
Vladis N, Coleman B
J Microbiol Biol Educ
. 2021 Oct;
22(2).
PMID: 34594468
While quantitative analytical skills have always been a part of modern biomedical training, the big data revolution and digital research environment have increased the importance of computational approaches for biomedical...
4.
Coleman B, Saha S, Sato S, Engelberg K, Ferguson D, Coppens I, et al.
mBio
. 2018 Oct;
9(5).
PMID: 30279285
Invasion of host cells by apicomplexan parasites such as is critical for their infectivity and pathogenesis. In , secretion of essential egress, motility, and invasion-related proteins from microneme organelles is...
5.
Saha S, Coleman B, Dubey R, Blader I, Gubbels M
mSphere
. 2017 Dec;
2(6).
PMID: 29202046
Paralogs of the widely prevalent phosphoglucomutase (PGM) protein called parafusin function in calcium (Ca)-mediated exocytosis across eukaryotes. In , the parafusin-related protein 1 (PRP1) has been associated with Ca-dependent microneme...
6.
Blader I, Coleman B, Chen C, Gubbels M
Annu Rev Microbiol
. 2015 Sep;
69:463-85.
PMID: 26332089
Toxoplasmosis is the clinical and pathological consequence of acute infection with the obligate intracellular apicomplexan parasite Toxoplasma gondii. Symptoms result from tissue destruction that accompanies lytic parasite growth. This review...
7.
Paul A, Saha S, Engelberg K, Jiang R, Coleman B, Kosber A, et al.
Cell Host Microbe
. 2015 Jun;
18(1):49-60.
PMID: 26118996
Apicomplexans invade a variety of metazoan host cells through mechanisms involving host cell receptor engagement and secretion of parasite factors to facilitate cellular attachment. We find that the parasite homolog...
8.
Coleman B, Skillman K, Jiang R, Childs L, Altenhofen L, Ganter M, et al.
Cell Host Microbe
. 2014 Aug;
16(2):177-186.
PMID: 25121747
The asexual forms of the malaria parasite Plasmodium falciparum are adapted for chronic persistence in human red blood cells, continuously evading host immunity using epigenetically regulated antigenic variation of virulence-associated...
9.
Farrell A, Coleman B, Benenati B, Brown K, Blader I, Marth G, et al.
BMC Genomics
. 2014 Jun;
15:354.
PMID: 24885922
Background: Next generation sequencing is helping to overcome limitations in organisms less accessible to classical or reverse genetic methods by facilitating whole genome mutational analysis studies. One traditionally intractable group,...
10.
Coleman B, Ribacke U, Manary M, Bei A, Winzeler E, Wirth D, et al.
Cell Host Microbe
. 2012 Dec;
12(6):739-50.
PMID: 23245319
Variation of surface adhesins, such as the Plasmodium falciparum erythrocyte invasion ligand PfRh4, is critical for virulence and immune evasion in many microbes. While phenotypic switching is linked to transcriptional...