Bert Maier
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Explore the profile of Bert Maier including associated specialties, affiliations and a list of published articles.
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25
Citations
1481
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Recent Articles
1.
Schmal C, Maier B, Ashwal-Fluss R, Bartok O, Finger A, Bange T, et al.
PLoS Biol
. 2023 Jun;
21(6):e3002164.
PMID: 37379316
A defining property of circadian clocks is temperature compensation, characterized by the resilience of their near 24-hour free-running periods against changes in environmental temperature within the physiological range. While temperature...
2.
Felten M, Ferencik S, Teixeira Alves L, Letsiou E, Lienau J, Muller-Redetzky H, et al.
Am J Respir Crit Care Med
. 2022 Dec;
207(11):1464-1474.
PMID: 36480958
Mechanical ventilation (MV) is life-saving but may evoke ventilator-induced lung injury (VILI). To explore how the circadian clock modulates severity of murine VILI via the core clock component BMAL1 (basic...
3.
Lang V, Ferencik S, Ananthasubramaniam B, Kramer A, Maier B
Elife
. 2021 Oct;
10.
PMID: 34661529
Local circadian clocks are active in most cells of our body. However, their impact on circadian physiology is still under debate. Mortality by endotoxic (LPS) shock is highly time-of-day dependent...
4.
Klemz S, Wallach T, Korge S, Rosing M, Klemz R, Maier B, et al.
Genes Dev
. 2021 Jul;
35(15-16):1161-1174.
PMID: 34301769
In all organisms with circadian clocks, post-translational modifications of clock proteins control the dynamics of circadian rhythms, with phosphorylation playing a dominant role. All major clock proteins are highly phosphorylated,...
5.
Gabriel C, Del Olmo M, Zehtabian A, Jager M, Reischl S, van Dijk H, et al.
Nat Commun
. 2021 Jun;
12(1):3796.
PMID: 34145278
The cell biology of circadian clocks is still in its infancy. Here, we describe an efficient strategy for generating knock-in reporter cell lines using CRISPR technology that is particularly useful...
6.
Maier B, Lorenzen S, Finger A, Herzel H, Kramer A
Methods Mol Biol
. 2020 Dec;
2130:103-114.
PMID: 33284439
RNA interference (RNAi) allows for the selective downregulation of gene expression by neutralizing targeted mRNA molecules and has frequently been used in high-throughput screening endeavors. Here, we describe a protocol...
7.
Bording T, Abdo A, Maier B, Gabriel C, Kramer A
Front Physiol
. 2019 May;
10:577.
PMID: 31143130
Circadian clocks are endogenous oscillators essential for orchestrating daily rhythms in physiology, metabolism and behavior. While mouse models have been instrumental to elucidate the molecular mechanism of circadian rhythm generation,...
8.
Wittenbrink N, Ananthasubramaniam B, Munch M, Koller B, Maier B, Weschke C, et al.
J Clin Invest
. 2018 Jun;
128(9):3826-3839.
PMID: 29953415
Background: The circadian clock is a fundamental and pervasive biological program that coordinates 24-hour rhythms in physiology, metabolism, and behavior, and it is essential to health. Whereas therapy adapted to...
9.
Korge S, Maier B, Bruning F, Ehrhardt L, Korte T, Mann M, et al.
PLoS Genet
. 2018 Jan;
14(1):e1007189.
PMID: 29377895
Circadian clocks are molecular timekeeping mechanisms that allow organisms to anticipate daily changes in their environment. The fundamental cellular basis of these clocks is delayed negative feedback gene regulation with...
10.
Gaspar L, Howald C, Popadin K, Maier B, Mauvoisin D, Moriggi E, et al.
Elife
. 2017 Sep;
6.
PMID: 28869038
The importance of natural gene expression variation for human behavior is undisputed, but its impact on circadian physiology remains mostly unexplored. Using umbilical cord fibroblasts, we have determined by genome-wide...