Benjamin Nicholson
Overview
Explore the profile of Benjamin Nicholson including associated specialties, affiliations and a list of published articles.
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Articles
48
Citations
2055
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0
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Recent Articles
1.
Jenkins K, Park M, Pederzoli-Ribeil M, Eskiocak U, Johnson P, Guzman W, et al.
J Immunother Cancer
. 2024 Jan;
11(12).
PMID: 38164757
Introduction: The clinical benefit of the anti-CTLA-4 monoclonal antibody (mAb) ipilimumab has been well established but limited by immune-related adverse events, especially when ipilimumab is used in combination with anti-PD-(L)1...
2.
Patel E, Malkova N, Crowe D, Pederzoli-Ribeil M, Fantini D, Fanny M, et al.
Mol Cancer Ther
. 2023 Nov;
23(4):421-435.
PMID: 38030380
IL12 is a proinflammatory cytokine, that has shown promising antitumor activity in humans by promoting the recruitment and activation of immune cells in tumors. However, the systemic administration of IL12...
3.
Salners T, Avila K, Nicholson B, Myers C, Beggs J, Dahmen K
Sci Rep
. 2023 Mar;
13(1):4871.
PMID: 36964158
A new statistical analysis of large neuronal avalanches observed in mouse and rat brain tissues reveals a substantial degree of recurrent activity and cyclic patterns of activation not seen in...
4.
Ibarra J, Elbanna Y, Kurylowicz K, Ciboddo M, Greenbaum H, Arellano N, et al.
Blood Cancer Discov
. 2022 Apr;
3(4):298-315.
PMID: 35405004
Significance: Current targeted therapies for CALR-mutated MPNs are not curative and fail to differentiate between type I- versus type II-driven disease. To improve treatment strategies, it is critical to identify...
5.
Trombetta B, Kandigian S, Kitchen R, Grauwet K, Webb P, Miller G, et al.
BMC Infect Dis
. 2021 Jul;
21(1):628.
PMID: 34210278
No abstract available.
6.
Trombetta B, Kandigian S, Kitchen R, Grauwet K, Webb P, Miller G, et al.
BMC Infect Dis
. 2021 Jun;
21(1):580.
PMID: 34134647
Background: COVID-19 has resulted in significant morbidity and mortality worldwide. Lateral flow assays can detect anti-Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) antibodies to monitor transmission. However, standardized evaluation of their...
7.
Quiroz R, Reutershan M, Schneider S, Sloman D, Lacey B, Swalm B, et al.
J Med Chem
. 2021 Mar;
64(7):3911-3939.
PMID: 33755451
Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyzes the post-translational symmetric dimethylation of protein substrates. PRMT5 plays a critical role in regulating biological processes including...
8.
Pancreatic circulating tumor cell profiling identifies LIN28B as a metastasis driver and drug target
Franses J, Philipp J, Missios P, Bhan I, Liu A, Yashaswini C, et al.
Nat Commun
. 2020 Jul;
11(1):3303.
PMID: 32620742
Pancreatic ductal adenocarcinoma (PDAC) lethality is due to metastatic dissemination. Characterization of rare, heterogeneous circulating tumor cells (CTCs) can provide insight into metastasis and guide development of novel therapies. Using...
9.
Allali-Hassani A, Szewczyk M, Ivanochko D, Organ S, Bok J, Ho J, et al.
Nat Commun
. 2019 Dec;
10(1):5759.
PMID: 31848333
PRDM9 is a PR domain containing protein which trimethylates histone 3 on lysine 4 and 36. Its normal expression is restricted to germ cells and attenuation of its activity results...
10.
Xu H, Muise E, Javaid S, Chen L, Cristescu R, Mansueto M, et al.
J Cell Mol Med
. 2019 Aug;
23(10):7063-7077.
PMID: 31449347
This study reports the establishment of a bone marrow mononuclear cell (BMMC) 3D culture model and the application of this model to define sensitivity and resistance biomarkers of acute myeloid...