Benjamin C Yen
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Explore the profile of Benjamin C Yen including associated specialties, affiliations and a list of published articles.
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Articles
5
Citations
153
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0
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Recent Articles
1.
Chatterjee S, Luthra P, Esaulova E, Agapov E, Yen B, Borek D, et al.
Nat Microbiol
. 2017 Jul;
2:17101.
PMID: 28665409
Human respiratory syncytial virus (hRSV) is a major cause of morbidity and mortality in the paediatric, elderly and immune-compromised populations. A gap in our understanding of hRSV disease pathology is...
2.
Luthra P, Aguirre S, Yen B, Pietzsch C, Sanchez-Aparicio M, Tigabu B, et al.
mBio
. 2017 Apr;
8(2).
PMID: 28377530
Ebola virus (EBOV) protein VP35 inhibits production of interferon alpha/beta (IFN) by blocking RIG-I-like receptor signaling pathways, thereby promoting virus replication and pathogenesis. A high-throughput screening assay, developed to identify...
3.
Yen B, Basler C
J Virol
. 2016 Mar;
90(10):5108-5118.
PMID: 26962215
Unlabelled: Dendritic cells (DCs) are major targets of filovirus infection in vivo Previous studies have shown that the filoviruses Ebola virus (EBOV) and Marburg virus (MARV) suppress DC maturation in...
4.
Liu C, Ye P, Yen B, Miao C
Mol Ther
. 2011 Apr;
19(8):1511-20.
PMID: 21468007
Generation of transgene-specific immune responses can constitute a major complication following gene therapy treatment. An in vivo approach to inducing selective expansion of Regulatory T (Treg) cells by injecting interleukin-2...
5.
Miao C, Harmeling B, Ziegler S, Yen B, Torgerson T, Chen L, et al.
Blood
. 2009 Aug;
114(19):4034-44.
PMID: 19713458
Gene transfer of a factor VIII (FVIII) plasmid into hemophilia A (HemA) mice achieved supraphysiologic FVIII expression, but triggered production of high-titer FVIII-specific antibodies and loss of functional FVIII activity....