Steven F Ziegler
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Explore the profile of Steven F Ziegler including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Dsilva A, Wagner A, Itan M, Rhone N, Avlas S, Gordon Y, et al.
bioRxiv
. 2025 Mar;
PMID: 40060399
Rationale: Thymic stromal lymphopoietin (TSLP) and IL-33 are alarmins implicated in EoE pathogenesis by activating multiple cells including mast cells (MCs). Whether TSLP or IL-33 have a role in EoE...
2.
Harada Y, Sasaki T, Obata-Ninomiya K, Matsuyama T, Ueha S, Shichino S, et al.
Res Sq
. 2025 Feb;
PMID: 39989951
Cutaneous allergen sensitization (CAS) underlies atopic dermatitis (AD) and leads to various allergic symptoms, including food allergy and anaphylaxis. IL-13 expression by T follicular helper T (T) has been reported...
3.
Obata-Ninomiya K, Jayaraman T, Ziegler S
Clin Transl Immunology
. 2024 Dec;
13(12):e70020.
PMID: 39654685
Type 2 epithelial cytokines, including thymic stromal lymphopoietin and IL-33, play central roles in modulation of type 2 immune cells, such as basophils. Basophils are a small subset of granulocytes...
4.
Hattori K, Tanaka S, Hashiba D, Tamura J, Etori K, Kageyama T, et al.
J Autoimmun
. 2024 Nov;
149:103333.
PMID: 39509740
Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic polyarthritis. It is well-established that helper T cells play crucial roles in the development and deterioration of RA. Recent studies...
5.
Domeier P, Ziegler S
J Leukoc Biol
. 2024 Oct;
117(2).
PMID: 39373526
Thymic stromal lymphopoietin is an established pleotropic alarmin cytokine that is generated at barrier tissues to induce type 2 immune responses, but its role in regulating the diversity of B...
6.
Weinstein K, Domeier P, Ziegler S
Int Immunol
. 2024 Aug;
37(2):83-90.
PMID: 39136284
Regulatory T cells (Tregs) are a specialized subset of CD4+ T cells essential for the maintenance of immune homeostasis and prevention of autoimmunity. Treg lineage and functions are programmed by...
7.
Jaeger N, Ulezko Antonova A, Kreisel D, Roan F, Lantelme E, Ziegler S, et al.
Nat Immunol
. 2024 Jul;
25(8):1460-1473.
PMID: 38956380
Group 1 innate lymphoid cells (ILC1s) are cytotoxic and interferon gamma-producing lymphocytes lacking antigen-specific receptors, which include ILC1s and natural killer (NK) cells. In mice, ILC1s differ from NK cells,...
8.
Chiu H, Weinstein K, Spath S, Hu A, Varela S, Obata-Ninomiya K, et al.
J Immunol
. 2024 May;
213(1):52-62.
PMID: 38767415
The thymus is an important site for the establishment of an appropriate immune response through positive and negative selection of developing T cells. During selection, developing T cells interact with...
9.
Malinczak C, Fonseca W, Hrycaj S, Morris S, Rasky A, Yagi K, et al.
Am J Physiol Lung Cell Mol Physiol
. 2024 Jan;
326(3):L280-L291.
PMID: 38290164
Early-life respiratory virus infections have been correlated with enhanced development of childhood asthma. In particular, significant numbers of respiratory syncytial virus (RSV)-hospitalized infants go on to develop lung disease. It...
10.
Norris G, Ames J, Ziegler S, Oberst A
PLoS Pathog
. 2023 Nov;
19(11):e1011350.
PMID: 37983247
In order to recover from infection, organisms must balance robust immune responses to pathogens with the tolerance of immune-mediated pathology. This balance is particularly critical within the central nervous system,...