Priya Luthra
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Explore the profile of Priya Luthra including associated specialties, affiliations and a list of published articles.
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Articles
33
Citations
1695
Followers
0
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Recent Articles
1.
Broeckel R, Browne A, Sucoloski S, Cantizani J, Simpson J, Pesiridis S, et al.
ACS Infect Dis
. 2024 Aug;
10(9):3392-3407.
PMID: 39207884
The emergence of SARS-CoV-2 and seasonal outbreaks of other respiratory viruses highlight the urgent need for broad-spectrum antivirals to treat respiratory tract infections. Stimulator of interferon genes (STING) is a...
2.
Unudurthi S, Luthra P, Bose R, McCarthy J, Kontaridis M
Life Sci
. 2020 Sep;
260:118482.
PMID: 32971105
Cardiovascular disease (CVD) is the most common co-morbidity associated with COVID-19 and the fatality rate in COVID-19 patients with CVD is higher compared to other comorbidities, such as hypertension and...
3.
Luthra P, Anantpadma M, De S, Sourimant J, Davey R, Plemper R, et al.
ACS Infect Dis
. 2020 Sep;
6(10):2783-2799.
PMID: 32870648
Marburg virus (MARV) causes sporadic outbreaks of severe disease with high case fatality rates in humans. To date, neither therapeutics nor prophylactic approaches have been approved for MARV disease. The...
4.
Williams C, Gibbons J, Keiffer T, Luthra P, Edwards M, Basler C
J Virol
. 2020 Apr;
94(13).
PMID: 32295912
Měnglà virus (MLAV), identified in bats, is a phylogenetically distinct member of the family Because the filoviruses Ebola virus (EBOV) and Marburg virus (MARV) modulate host innate immunity, MLAV VP35,...
5.
Woolsey C, Menicucci A, Cross R, Luthra P, Agans K, Borisevich V, et al.
Cell Rep
. 2019 Sep;
28(12):3032-3046.e6.
PMID: 31533029
Zaire ebolavirus (EBOV) VP35 protein is a suppressor of type I interferon (IFN) production, an inhibitor of dendritic cell maturation, and a putative virulence determinant. Here, a recombinant EBOV encoding...
6.
Lim H, Huang S, Chen J, Kerner G, Gilliaux O, Bastard P, et al.
J Exp Med
. 2019 Jun;
216(9):2038-2056.
PMID: 31217193
Autosomal recessive IRF7 and IRF9 deficiencies impair type I and III IFN immunity and underlie severe influenza pneumonitis. We report three unrelated children with influenza A virus (IAV) infection manifesting...
7.
Amatya P, Wagner N, Chen G, Luthra P, Shi L, Borek D, et al.
ACS Infect Dis
. 2019 May;
5(8):1385-1396.
PMID: 31120240
Marburg virus causes sporadic outbreaks of severe hemorrhagic fever with high case fatality rates. Approved, effective, and safe therapeutic or prophylactic countermeasures are lacking. To address this, we used phage...
8.
Batra J, Hultquist J, Liu D, Shtanko O, Von Dollen J, Satkamp L, et al.
Cell
. 2018 Dec;
175(7):1917-1930.e13.
PMID: 30550789
Ebola virus (EBOV) infection often results in fatal illness in humans, yet little is known about how EBOV usurps host pathways during infection. To address this, we used affinity tag-purification...
9.
Luthra P, Naidoo J, Pietzsch C, De S, Khadka S, Anantpadma M, et al.
Antiviral Res
. 2018 Aug;
158:288-302.
PMID: 30144461
Specific host pathways that may be targeted therapeutically to inhibit the replication of Ebola virus (EBOV) and other emerging viruses remain incompletely defined. A screen of 200,000 compounds for inhibition...
10.
Edwards M, Liu H, Shabman R, Ginell G, Luthra P, Ramanan P, et al.
Cell Rep
. 2018 Jul;
24(4):861-872.e6.
PMID: 30044983
Non-retroviral integrated RNA viral sequences (NIRVs) potentially encoding ∼280 amino acid homologs to filovirus VP35 proteins are present across the Myotis genus of bats. These are estimated to have been...