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Benjamin A Alman

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Articles 126
Citations 4904
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Recent Articles
1.
Tani S, Ishikawa K, Chiapparelli E, Camino-Willhuber G, Schonnagel L, Caffard T, et al.
J Orthop Res . 2025 Feb; PMID: 39904732
Assessing the bone condition in patients with spinal disease is clinically valuable. However, evaluating bone strength in the presence of spine degenerative changes is challenging. Quantitative computed tomography (QCT) and...
2.
Puviindran V, Shimada E, Huang Z, Ma X, Ban G, Xiang Y, et al.
Sci Rep . 2024 Nov; 14(1):26208. PMID: 39482341
Enchondromas are a common tumor in bone that can occur as multiple lesions in enchondromatosis, which is associated with deformity of the affected bone. These lesions harbor somatic mutations in...
3.
Ban G, Puviindran V, Xiang Y, Nadesan P, Tang J, Ou J, et al.
iScience . 2024 Jul; 27(7):110187. PMID: 38989451
Intratumoral heterogeneity is common in cancer, particularly in sarcomas like undifferentiated pleomorphic sarcoma (UPS), where individual cells demonstrate a high degree of cytogenic diversity. Previous studies showed that a small...
4.
Puviindran V, Shimada E, Huang Z, Ma X, Ban G, Xiang Y, et al.
Res Sq . 2024 Jun; PMID: 38883785
Enchondromas are a common tumor in bone that can occur as multiple lesions in enchondromatosis, which is associated with deformity of the effected bone. These lesions harbor mutations in and...
5.
Al-Jazrawe M, Xu S, Poon R, Wei Q, Przybyl J, Varma S, et al.
Cancer Res Commun . 2023 Jun; 3(4):697-708. PMID: 37377751
Significance: Distinguishing between neoplastic (tumor) and non-neoplastic (stromal) cells within mesenchymal tumors is particularly challenging, because lineage-specific cell surface markers typically used in other cancers do not differentiate between the...
6.
Pathmanapan S, Poon R, De Renshaw T, Nadesan P, Nakagawa M, Seesankar G, et al.
Cell Rep . 2023 Jun; 42(6):112578. PMID: 37267108
Chondrosarcomas are the most common malignancy of cartilage and are associated with somatic mutations in isocitrate dehydrogenase 1 (IDH1) and IDH2 genes. Somatic IDH mutations are also found in its...
7.
Sessler D, Alman B, Treggiari M, Mont M
J Arthroplasty . 2023 May; 38(6):986-991. PMID: 37211379
PRO: Nearly all new devices and drugs come from industry that provides two-thirds of the funding for medical research, and a much higher fraction of clinical research. Realistically, without corporate-funded...
8.
Ito K, Nishida Y, Hamada S, Shimizu K, Sakai T, Ohkawara B, et al.
Sci Rep . 2022 Jul; 12(1):11918. PMID: 35831372
Anticancer drugs and molecular targeted therapies are used for refractory desmoid-type fibromatosis (DF), but occasionally cause severe side effects. The purpose of this study was to identify an effective drug...
9.
Yahara Y, Nguyen T, Ishikawa K, Kamei K, Alman B
Development . 2022 May; 149(8). PMID: 35502779
The mechanisms underlying bone development, repair and regeneration are reliant on the interplay and communication between osteoclasts and other surrounding cells. Osteoclasts are multinucleated monocyte lineage cells with resorptive abilities,...
10.
Mu L, Wang Y, Hu Y, Shi C, Alman B, Zhang C, et al.
Genet Test Mol Biomarkers . 2022 Apr; 26(4):174-183. PMID: 35481970
Colorectal cancer (CRC) is one of the leading causes of cancer-related death, and up to 50% of individuals will suffer relapse. Although transmembrane and immunoglobulin domain-containing protein 1 (TMIGD1) was...