Ben C Tilly
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Explore the profile of Ben C Tilly including associated specialties, affiliations and a list of published articles.
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11
Citations
123
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Recent Articles
1.
Wolf van der Meer J, Larue A, van der Knaap J, Chalkley G, Sijm A, Beikmohammadi L, et al.
Genes Dev
. 2025 Feb;
39(5-6):401-422.
PMID: 39919828
Pathogenic variants in the ubiquitin-specific protease 7 () gene cause a neurodevelopmental disorder called Hao-Fountain syndrome. However, it remains unclear which of USP7's pleiotropic functions are relevant for neurodevelopment. Here,...
2.
Tilly B, Chalkley G, van der Knaap J, Moshkin Y, Kan T, Dekkers D, et al.
Elife
. 2021 Jul;
10.
PMID: 34313222
ATP-dependent chromatin remodelers control the accessibility of genomic DNA through nucleosome mobilization. However, the dynamics of genome exploration by remodelers, and the role of ATP hydrolysis in this process remain...
3.
De Jonge H, Tilly B, Hogema B, Pfau D, Kelley C, Kelley M, et al.
Am J Physiol Cell Physiol
. 2013 Nov;
306(4):C343-53.
PMID: 24259420
The in vitro perfused rectal gland of the dogfish shark (Squalus acanthias) and filter-grown monolayers of primary cultures of shark rectal gland (SRG) epithelial cells were used to analyze the...
4.
Tomassen S, De Jonge H, Tilly B
Adv Exp Med Biol
. 2008 Aug;
559:339-47.
PMID: 18727253
No abstract available.
5.
Lim C, Bot A, De Jonge H, Tilly B
Methods Enzymol
. 2007 Sep;
428:325-42.
PMID: 17875427
Most cells have to perform their physiological functions under a variable osmotic stress, which, because of the relatively high permeability of the plasma membrane for water, may result in frequent...
6.
Cholesterol depletion and genistein as tools to promote F508delCFTR retention at the plasma membrane
Lim C, Bijvelds M, Nigg A, Schoonderwoerd K, Houtsmuller A, De Jonge H, et al.
Cell Physiol Biochem
. 2007 Sep;
20(5):473-82.
PMID: 17762174
Background/aims: F508delCFTR-, but not wtCFTR-, expressing fibroblasts resemble Niemann Pick type C cells in the massive intracellular accumulation of free cholesterol. The recruitment and activation of F508delCFTR by cholesterol depletion...
7.
Furst J, Schedlbauer A, Gandini R, Garavaglia M, Saino S, Gschwentner M, et al.
J Biol Chem
. 2005 May;
280(35):31276-82.
PMID: 15905169
ICln is a multifunctional protein involved in regulatory mechanisms as different as membrane ion transport and RNA splicing. The protein is water-soluble, and during regulatory volume decrease after cell swelling,...
8.
Tomassen S, van der Wijk T, De Jonge H, Tilly B
FEBS Lett
. 2004 May;
566(1-3):287-90.
PMID: 15147910
In response to osmotic cell swelling, Intestine 407 cells react with a rapid and transient activation of phospholipase D (PLD). To investigate the role of PLD during the regulatory volume...
9.
Tomassen S, Fekkes D, De Jonge H, Tilly B
Am J Physiol Cell Physiol
. 2004 Feb;
286(6):C1417-22.
PMID: 14960416
Human Intestine 407 cells respond to osmotic cell swelling by the activation of Cl(-)- and K(+)-selective ionic channels, as well as by stimulating an organic osmolyte release pathway readily permeable...
10.
Verloo P, Kocken C, van der Wel A, Tilly B, Hogema B, Sinaasappel M, et al.
J Biol Chem
. 2003 Dec;
279(11):10316-22.
PMID: 14679190
An inwardly rectifying anion channel in malaria-infected red blood cells has been proposed to function as the "new permeation pathway" for parasite nutrient acquisition. As the channel shares several properties...