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Bart P Braeckman

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Articles 82
Citations 2025
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Recent Articles
1.
Wu P, Vandemeulebroucke L, Claeys M, Bert W, Braeckman B
J Gerontol A Biol Sci Med Sci . 2024 Aug; 79(11). PMID: 39171522
Axenic dietary restriction (ADR) is highly effective in extending lifespan of Caenorhabditis elegans, but its effects on healthspan improvement are less well characterized. Using transmission electron microscopy, morphometric analyses, and...
2.
Koutsoumparis A, Busack I, Chen C, Hayashi Y, Braeckman B, Meierhofer D, et al.
Genetics . 2023 Sep; 225(2). PMID: 37682641
Sleep is a fundamental state of behavioral quiescence and physiological restoration. Sleep is controlled by environmental conditions, indicating a complex regulation of sleep by multiple processes. Our knowledge of the...
3.
Jushaj A, Churgin M, De La Torre M, Kieswetter A, Driesschaert B, Dhondt I, et al.
Biogerontology . 2023 Jan; 24(2):225-233. PMID: 36662373
Understanding how we can age healthily is a challenge at the heart of biogerontological interest. Whereas myriad genes are known to affect the lifespan of model organisms, effects of such...
4.
Hafideddine Z, Loier T, Van Brempt N, De Henau S, Ching H, Neukermans S, et al.
J Inorg Biochem . 2022 Nov; 238:112063. PMID: 36370505
The popular genetic model organism Caenorhabditis elegans (C. elegans) encodes 34 globins, whereby the few that are well-characterized show divergent properties besides the typical oxygen carrier function. Here, we present...
5.
Cai H, Wu P, Vandemeulebroucke L, Dhondt I, Rasulova M, Vierstraete A, et al.
Int J Mol Sci . 2022 Oct; 23(19). PMID: 36232823
Axenically cultured show many characteristic traits of worms subjected to dietary restriction, such as slowed development, reduced fertility, and increased stress resistance. Hence, the term axenic dietary restriction (ADR) is...
6.
De Spiegeleer A, Wynendaele E, Descamps A, Debunne N, Braeckman B, De Mey M, et al.
Clin Transl Med . 2022 Oct; 12(10):e1053. PMID: 36229976
No abstract available.
7.
Saul N, Dhondt I, Kuokkanen M, Perola M, Verschuuren C, Wouters B, et al.
Biogerontology . 2022 Jun; 23(4):431-452. PMID: 35748965
To find drivers of healthy ageing, a genome-wide association study (GWAS) was performed in healthy and unhealthy older individuals. Healthy individuals were defined as free from cardiovascular disease, stroke, heart...
8.
Vierstraete A, Braeckman B
Ecol Evol . 2022 Mar; 12(3):e8603. PMID: 35261737
Oxford Nanopore Technologies (ONT) is a third-generation sequencing technology that is gaining popularity in ecological research for its portable and low-cost sequencing possibilities. Although the technology excels at long-read sequencing,...
9.
Zecic A, Dhondt I, Braeckman B
Cells . 2022 Jan; 11(2). PMID: 35053361
DAF-16-dependent activation of a dauer-associated genetic program in the insulin/IGF-1 mutant leads to accumulation of large amounts of glycogen with concomitant upregulation of glycogen synthase, GSY-1. Glycogen is a major...
10.
Dhondt I, Verschuuren C, Zecic A, Loier T, Braeckman B, De Vos W
Dis Model Mech . 2021 Nov; 14(11). PMID: 34723324
Sarcopenia encompasses a progressive decline in muscle quantity and quality. Given its close association with ageing, it may represent a valuable healthspan marker. The commonalities with human muscle structure and...