Barry Hart
Overview
Explore the profile of Barry Hart including associated specialties, affiliations and a list of published articles.
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10
Citations
240
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0
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Recent Articles
1.
Szalanczy A, Sherrill C, Fanning K, Hart B, Caudell D, Davis A, et al.
Radiat Res
. 2024 May;
202(1):1-10.
PMID: 38772553
As the number of cancer survivors increases and the risk of accidental radiation exposure rises, there is a pressing need to characterize the delayed effects of radiation exposure and develop...
2.
Nemec-Bakk A, Sridharan V, Desai P, Landes R, Hart B, Allen A, et al.
Life (Basel)
. 2023 Mar;
13(3).
PMID: 36983950
Missions into deep space will expose astronauts to the harsh space environment, and the degenerative tissue effects of space radiation are largely unknown. To assess the risks, in this study,...
3.
Fish B, Hart B, Gasperetti T, Narayanan J, Gao F, Veley D, et al.
Int J Radiat Biol
. 2023 Feb;
99(7):1119-1129.
PMID: 36794325
Purpose: To test IPW-5371 for the mitigation of the delayed effects of acute radiation exposure (DEARE). Survivors of acute radiation exposure are at risk for developing delayed multi-organ toxicities; however,...
4.
Fish B, MacVittie T, Gao F, Narayanan J, Gasperetti T, Scholler D, et al.
Health Phys
. 2021 Sep;
121(4):419-433.
PMID: 34546222
The goal of this study was to develop rat models of partial body irradiation with bone-marrow sparing (leg-out PBI) to test medical countermeasures (MCM) of both acute radiation syndrome (ARS)...
5.
Senatorov Jr V, Friedman A, Milikovsky D, Ofer J, Saar-Ashkenazy R, Charbash A, et al.
Sci Transl Med
. 2019 Dec;
11(521).
PMID: 31801886
Aging involves a decline in neural function that contributes to cognitive impairment and disease. However, the mechanisms underlying the transition from a young-and-healthy to aged-and-dysfunctional brain are not well understood....
6.
IPW-5371 Proves Effective as a Radiation Countermeasure by Mitigating Radiation-Induced Late Effects
Rabender C, Mezzaroma E, Mauro A, Mullangi R, Abbate A, Anscher M, et al.
Radiat Res
. 2016 Nov;
186(5):478-488.
PMID: 27841740
There is an ongoing and significant need for radiation countermeasures to reduce morbidities and mortalities associated with exposure of the heart and lungs from a radiological or nuclear incidents. Radiation-induced...
7.
Kumar D, Rai R, Brameld K, Riggs J, Somoza J, Rajagopalan R, et al.
Bioorg Med Chem Lett
. 2011 Nov;
22(1):300-4.
PMID: 22119470
The discovery and optimization of a novel class of quinolone small-molecules that inhibit NS5B polymerase, a key enzyme of the HCV viral life-cycle, is described. Our research led to the...
8.
Malerich J, Lam J, Hart B, Fine R, Klebansky B, Tanga M, et al.
Bioorg Med Chem Lett
. 2010 Nov;
20(24):7454-7.
PMID: 21106455
Tyrosine kinase 2 (TYK2) is required for signaling of interleukin-23 (IL-23), which plays a key role in rheumatoid arthritis. Presented is the design and synthesis of 1,2,4-triazoles, and the evaluation...
9.
Haynes D, Brodie J, Waterhouse J, Bainbridge Z, Bass D, Hart B
Environ Manage
. 2007 Sep;
40(6):993-1003.
PMID: 17786511
Run-off containing increased concentrations of sediment, nutrients, and pesticides from land-based anthropogenic activities is a significant influence on water quality and the ecologic conditions of nearshore areas of the Great...
10.
Tran T, Uhl M, Ma J, Janssen L, Sriram V, Aulwurm S, et al.
Neuro Oncol
. 2007 May;
9(3):259-70.
PMID: 17522330
Transforming growth factor-beta (TGF-beta) is a proinvasive and immunosuppressive cytokine that plays a major role in the malignant phenotype of gliomas. One novel strategy of disabling TGF-beta activity in gliomas...