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Jayashree Narayanan

Explore the profile of Jayashree Narayanan including associated specialties, affiliations and a list of published articles. Areas
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Articles 29
Citations 383
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Recent Articles
1.
Kondelaji M, Sharma G, Jagtap J, Shafiee S, Hansen C, Gasperetti T, et al.
Mol Imaging Biol . 2023 Aug; 26(1):124-137. PMID: 37530966
Purpose: Vascular endothelium plays a central role in the pathogenesis of acute and chronic radiation injuries, yet the mechanisms which promote sustained endothelial dysfunction and contribute to late responding organ...
2.
Medhora M, Gao F, Gasperetti T, Narayanan J, Himburg H, Jacobs E, et al.
Int J Mol Sci . 2023 Mar; 24(6). PMID: 36982722
Currently, there are no biomarkers to predict lethal lung injury by radiation. Since it is not ethical to irradiate humans, animal models must be used to identify biomarkers. Injury to...
3.
Fish B, Hart B, Gasperetti T, Narayanan J, Gao F, Veley D, et al.
Int J Radiat Biol . 2023 Feb; 99(7):1119-1129. PMID: 36794325
Purpose: To test IPW-5371 for the mitigation of the delayed effects of acute radiation exposure (DEARE). Survivors of acute radiation exposure are at risk for developing delayed multi-organ toxicities; however,...
4.
Mostaghimi S, Mehrvar S, Foomani F, Narayanan J, Fish B, Camara A, et al.
Biomed Opt Express . 2022 Aug; 13(8):4338-4352. PMID: 36032582
Though angiogenesis has been investigated in depth, vascular regression and rarefaction remain poorly understood. Regression of renal vasculature accompanies many pathological states such as diabetes, hypertension, atherosclerosis, and radiotherapy. Radiation...
5.
Gasperetti T, Sharma G, Frei A, Pierce L, Veley D, Szalewski N, et al.
Radiat Res . 2022 Jul; 198(4):325-335. PMID: 35904437
The renin-angiotensin system (RAS) is known to regulate the pathogenesis of radiation-induced injury as inhibitors of the RAS enzyme angiotensin converting enzyme (ACE) have established function as mitigators of multi-organ...
6.
Ortiz de Choudens S, Sparapani R, Narayanan J, Lohr N, Gao F, Fish B, et al.
Front Oncol . 2022 Mar; 12:828177. PMID: 35311118
The genetic bases and disparate responses to radiotherapy are poorly understood, especially for cardiotoxicity resulting from treatment of thoracic tumors. Preclinical animal models such as the Dahl salt-sensitive (SS) rat...
7.
Sharma G, Fish B, Frei A, Narayanan J, Gasperetti T, Scholler D, et al.
Int J Radiat Oncol Biol Phys . 2022 Jan; 113(1):177-191. PMID: 35093482
Purpose: Radiation-induced lung injury is a major dose-limiting toxicity for thoracic radiation therapy patients. In experimental models, treatment with angiotensin converting enzyme (ACE) inhibitors mitigates radiation pneumonitis; however, the mechanism...
8.
Sharma G, Frei A, Narayanan J, Gasperetti T, Veley D, Amjad A, et al.
PLoS One . 2021 Oct; 16(10):e0259042. PMID: 34695155
Brain-derived neurotrophic factor (BDNF) is a member of the nerve growth factor family which has been extensively studied for its roles in neural development, long-term memory, brain injury, and neurodegenerative...
9.
Fish B, MacVittie T, Gao F, Narayanan J, Gasperetti T, Scholler D, et al.
Health Phys . 2021 Sep; 121(4):419-433. PMID: 34546222
The goal of this study was to develop rat models of partial body irradiation with bone-marrow sparing (leg-out PBI) to test medical countermeasures (MCM) of both acute radiation syndrome (ARS)...
10.
Gasperetti T, Miller T, Gao F, Narayanan J, Jacobs E, Szabo A, et al.
Front Pharmacol . 2021 Sep; 12:741485. PMID: 34512365
[This corrects the article DOI: 10.3389/fphar.2021.634477.].