Barbel Rohrer
Overview
Explore the profile of Barbel Rohrer including associated specialties, affiliations and a list of published articles.
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93
Citations
7916
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Recent Articles
11.
Navneet S, Rohrer B
Exp Eye Res
. 2022 Jul;
222:109164.
PMID: 35798060
The extracellular matrix (ECM) and its turnover play a crucial role in the pathogenesis of several inflammatory diseases, including age-related macular degeneration (AMD). Elastin, a critical protein component of the...
12.
Akter T, Annamalai B, Obert E, Simpson K, Rohrer B
Front Immunol
. 2022 Jul;
13:896274.
PMID: 35784301
Background: Age-related macular degeneration (AMD), the leading cause of irreversible blindness in elderly Caucasian populations, includes destruction of the blood-retina barrier (BRB) generated by the retinal pigment epithelium-Bruch's membrane complex...
13.
Csaky K, Curcio C, Mullins R, Rosenfeld P, Fujimoto J, Rohrer B, et al.
Exp Eye Res
. 2022 Jun;
221:109134.
PMID: 35654115
No abstract available.
14.
Rohrer B, Parsons N, Annamalai B, Nicholson C, Obert E, Jones B, et al.
Exp Eye Res
. 2021 Sep;
212:108755.
PMID: 34487725
Purpose: Age-related macular degeneration (AMD), the leading cause of blindness in western populations, is associated with an overactive complement system, and an increase in circulating antibodies against certain epitopes, including...
15.
Ishii M, Beeson G, Beeson C, Rohrer B
Methods Mol Biol
. 2021 Jun;
2277:423-431.
PMID: 34080166
Intracellular Ca is strictly regulated to maintain optimal levels for function of cellular organelles as well as mitochondrial respiratory signaling at the tricarboxylic acid cycle and electron transport chain level....
16.
Rohrer B, Biswal M, Obert E, Dang Y, Su Y, Zuo X, et al.
Int J Mol Sci
. 2021 Jun;
22(10).
PMID: 34064901
To characterize the mechanisms by which the highly conserved exocyst trafficking complex regulates eye physiology in zebrafish and mice, we focused on Exoc5 (also known as ), a central exocyst...
17.
Beeson C, Peterson Y, Perron N, Bandyopadhyay M, Nasarre C, Beeson G, et al.
J Ocul Pharmacol Ther
. 2021 May;
37(6):367-378.
PMID: 33945330
Metabolic stress and associated mitochondrial dysfunction are implicated in retinal degeneration irrespective of the underlying cause. We identified seven unique chemicals from a Chembridge DiverSET screen and tested their protection...
18.
Annamalai B, Parsons N, Nicholson C, Joseph K, Coughlin B, Yang X, et al.
Exp Eye Res
. 2021 Apr;
207:108583.
PMID: 33878326
Purpose: Age-related macular degeneration is a slowly progressing disease. Studies have tied disease risk to an overactive complement system. We have previously demonstrated that pathology in two mouse models, the...
19.
Annamalai B, Parsons N, Nicholson C, Obert E, Jones B, Rohrer B
Invest Ophthalmol Vis Sci
. 2021 Apr;
62(4):11.
PMID: 33830174
Purpose: The risk for age-related macular degeneration has been tied to an overactive complement system. Despite combined attempts by academia and industry to develop therapeutics that modulate the complement response,...
20.
Ishii M, Beeson G, Beeson C, Rohrer B
Front Immunol
. 2021 Mar;
12:628062.
PMID: 33746964
Complement component 3 fragment C3a is an anaphylatoxin involved in promoting cellular responses important in immune response and host defense. Its receptor (C3a receptor, C3aR) is distributed on the plasma...