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Balasubramanyam Karanam

Explore the profile of Balasubramanyam Karanam including associated specialties, affiliations and a list of published articles. Areas
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Articles 50
Citations 1492
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Recent Articles
1.
Jin F, Thaiparambil J, Donepudi S, Vantaku V, Piyarathna D, Maity S, et al.
Cancer Prev Res (Phila) . 2024 Jun; 17(6):281. PMID: 38831722
No abstract available.
2.
White J, Kaninjing E, Adeniji K, Jibrin P, Obafunwa J, Ogo C, et al.
Prostate . 2024 Jan; 84(5):460-472. PMID: 38192023
Background: Through whole-exome sequencing of 60 formalin-fixed paraffin-embedded Nigerian (NGRn) benign prostatic hyperplasia (BPH) samples, we identified germline and somatic alterations in apoptotic pathways impacting BPH development and progression. Prostate...
3.
Anchoori R, Anchoori V, Lam B, Tseng S, Das S, Velasquez F, et al.
PLoS One . 2023 Jun; 18(6):e0285221. PMID: 37315065
Bortezomib has been successful for treatment of multiple myeloma, but not against solid tumors, and toxicities of neuropathy, thrombocytopenia and the emergence of resistance have triggered efforts to find alternative...
4.
Ghebremedhin A, Bin Salam A, Adu-Addai B, Noonan S, Stratton R, Ahmed M, et al.
Cells . 2023 May; 12(9). PMID: 37174654
Activated M2-polarized macrophages are drivers of pulmonary fibrosis in several clinical scenarios, including Idiopathic Pulmonary Fibrosis (IPF). In this study, we investigated the effects of targeting the CD206 receptor in...
5.
Siddappa M, Hussain S, Wani S, White J, Tang H, Gray J, et al.
Cancer Res Commun . 2023 Apr; 3(4):621-639. PMID: 37082578
Significance: Our study identified that genomic ancestry drives the VDR complex composition, genomic distribution, and transcriptional function, and is disrupted by BAZ1A and illustrates a novel driver for AA prostate...
6.
White J, Kaninjing E, Adeniji K, Jibrin P, Obafunwa J, Ogo C, et al.
Cancer Res Commun . 2023 Mar; 2(9):1005-1016. PMID: 36922933
Significance: MAA have higher rates of prostate cancer incidence and mortality, however, are severely underrepresented in genomic studies. This is the first study utilizing whole-exome sequencing in NG men to...
7.
Martini R, Delpe P, Chu T, Arora K, Lord B, Verma A, et al.
Cancer Discov . 2022 Sep; 12(11):2530-2551. PMID: 36121736
Significance: Our comprehensive ancestry quantification process revealed that ancestry-associated gene expression profiles in TNBC include population-level distinctions in immunologic landscapes. These differences may explain some differences in race-group clinical outcomes....
8.
Tamang N, Andrews C, Mavileti S, Nanduri S, Golakoti N, Karanam B
New J Chem . 2022 Sep; 46(20):9745-9754. PMID: 36093125
Acetals (, , and ) of andrographolide (), 14-deoxy-12-hydroxyandrographolide (), and isoandrographolide () were synthesized using benzaldehyde and heteroaromatic aldehydes. All the synthesized derivatives were characterized using H-NMR, C-NMR, mass...
9.
Mori J, White J, Elhussin I, Duduyemi B, Karanam B, Yates C, et al.
Front Oncol . 2022 Aug; 12:928357. PMID: 36033462
Prostate cancer (PCa) disproportionately affects African American (AA) men, yet present biomarkers do not address the observed racial disparity. The objective of this study was to identify biomarkers with potential...
10.
Kalra R, Chen C, Wang J, Bin Salam A, Dobrolecki L, Lewis A, et al.
Cancer Res . 2022 Jun; 82(16):2928-2939. PMID: 35736563
Significance: Evaluation of the functional impact of HER2 mutations on therapy-induced resistance and metastasis identifies robust antitumor activity of poziotinib and supports the clinical evaluation of poziotinib in ER+ HER2...