Axel J Scheidig
Overview
Explore the profile of Axel J Scheidig including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
47
Citations
490
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Klopp C, Zhang X, Campbell M, Kvaskoff D, Struwe M, Warren C, et al.
J Med Chem
. 2024 Oct;
67(20):18090-18097.
PMID: 39397364
-Hydroxyurea has been known since the 1960s as an antiproliferative drug and is used both in oncology and for treatment of hematological disorders such as sickle cell anemia where very...
2.
Struwe M, Yang J, Kolanji K, Mengell J, Scheidig A, Clement B, et al.
Inorg Chem
. 2024 Oct;
63(41):19063-19073.
PMID: 39350518
A combination of X-ray absorption and low-temperature electronic absorption spectroscopies has been used to probe the geometric and electronic structures of the human mitochondrial amidoxime reducing component enzyme (hmARC1) in...
3.
Zhang N, Li L, Mohri M, Siebert S, Lutteke T, Louton H, et al.
Int J Biol Macromol
. 2024 Aug;
279(Pt 1):134951.
PMID: 39179069
The structural dynamics of the interactions between defensins or lysozymes and various saccharide chains that are covalently linked to lipids or proteins were analyzed in relation to the sub-molecular architecture...
4.
Jones A, Bajrami B, Campbell M, Erzurumluoglu A, Guo Q, Chen H, et al.
Hepatol Commun
. 2024 Apr;
8(5).
PMID: 38619429
Background: Mutations in the gene MTARC1 (mitochondrial amidoxime-reducing component 1) protect carriers from metabolic dysfunction-associated steatohepatitis (MASH) and cirrhosis. MTARC1 encodes the mARC1 enzyme, which is localized to the mitochondria...
5.
Struwe M, Scheidig A, Clement B
J Biol Chem
. 2023 Oct;
299(11):105306.
PMID: 37778733
The mitochondrial amidoxime-reducing component (mARC) is one of five known molybdenum enzymes in eukaryotes. mARC belongs to the MOSC domain superfamily, a large group of so far poorly studied molybdoenzymes....
6.
Rixen S, Indorf P, Kubitza C, Struwe M, Klopp C, Scheidig A, et al.
Molecules
. 2023 Sep;
28(17).
PMID: 37687214
The mitochondrial amidoxime reducing component (mARC) is a human molybdoenzyme known to catalyze the reduction of various -oxygenated substrates. The physiological function of mARC enzymes, however, remains unknown. In this...
7.
Klopp C, Struwe M, Plieth C, Clement B, Scheidig A
Anal Chem
. 2023 Aug;
95(33):12452-12458.
PMID: 37549068
The mitochondrial amidoxime-reducing component (mARC) is one of the simplest molybdenum-containing enzymes. mARC is among a few known reducing enzymes playing an important role in drug metabolism in mammals. Here,...
8.
Krohn S, Boje A, Gehlert C, Lutz S, Darzentas N, Knecht H, et al.
Front Immunol
. 2022 Jul;
13:908093.
PMID: 35784366
To identify new antibodies for the treatment of plasma cell disorders including multiple myeloma (MM), a single-chain Fragment variable (scFv) antibody library was generated by immunizing mice with patient-derived malignant...
9.
Oetke S, Scheidig A, Krupinska K
Plant Cell Physiol
. 2021 Nov;
63(2):234-247.
PMID: 34792609
WHIRLY1 in barley was shown to be a major architect of plastid nucleoids. Its accumulation in cells of Escherichia coli coincided with an induction of nucleoid compaction and growth retardation....
10.
Helfrich F, Scheidig A
Acta Crystallogr D Struct Biol
. 2021 Oct;
77(Pt 10):1317-1335.
PMID: 34605434
Polyamines influence medically relevant processes in the opportunistic pathogen Pseudomonas aeruginosa, including virulence, biofilm formation and susceptibility to antibiotics. Although homospermidine synthase (HSS) is part of the polyamine metabolism in...