Sebastian Krossa
Overview
Explore the profile of Sebastian Krossa including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
137
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0
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Recent Articles
1.
Kiviaho A, Eerola S, Kallio H, Andersen M, Hoikka M, Tiihonen A, et al.
Nat Commun
. 2024 Nov;
15(1):9949.
PMID: 39550375
Prostate cancer treatment resistance is a significant challenge facing the field. Genomic and transcriptomic profiling have partially elucidated the mechanisms through which cancer cells escape treatment, but their relation toward...
2.
Andersen M, Krossa S, Midtbust E, Pedersen C, Wess M, Hoiem T, et al.
Commun Biol
. 2024 Nov;
7(1):1462.
PMID: 39511287
Prostate tumor heterogeneity is a major obstacle when studying the biological mechanisms of molecular markers. Increased gene expression levels of secreted frizzled-related protein 4 (SFRP4) is a biomarker in aggressive...
3.
Giampa M, Andersen M, Krossa S, Denti V, Smith A, Moestue S
Methods Mol Biol
. 2023 Jul;
2688:161-172.
PMID: 37410292
Molecular visualization of metabolites, lipids, and proteins by matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI MSI) is becoming an in-demand analytical approach to aid the histopathological analysis of breast cancer....
4.
Andersen M, Giampa M, Midtbust E, Hoiem T, Krossa S, Tessem M
Methods Mol Biol
. 2023 Jul;
2688:135-146.
PMID: 37410290
Metabolites reflect the biological state of cells and tissue, and metabolomics is therefore a field of high interest both to understand normal physiological functions and disease development. When studying heterogeneous...
5.
Rye M, Krossa S, Hall M, van Mourik C, Bathen T, Drablos F, et al.
iScience
. 2022 Jun;
25(6):104451.
PMID: 35707723
High secretion of the metabolites citrate and spermine is a unique hallmark for normal prostate epithelial cells, and is reduced in aggressive prostate cancer. However, the identity of the genes...
6.
Buchholz R, Krossa S, Andersen M, Holtkamp M, Sperling M, Karst U, et al.
Metallomics
. 2022 Mar;
14(3).
PMID: 35294013
A rapid and cost-efficient tissue preparation protocol for laser ablation-inductively coupled plasma-mass spectrometry imaging (LA-ICP-MSI) has been developed within this study as an alternative to the current gold standard using...
7.
Hoiem T, Andersen M, Martin-Lorenzo M, Longuespee R, Claes B, Nordborg A, et al.
Proteomics
. 2022 Feb;
22(10):e2100223.
PMID: 35170848
MALDI MS imaging (MSI) is a powerful analytical tool for spatial peptide detection in heterogeneous tissues. Proper sample preparation is crucial to achieve high quality, reproducible measurements. Here we developed...
8.
Andersen M, Hoiem T, Claes B, Balluff B, Martin-Lorenzo M, Richardsen E, et al.
Cancer Metab
. 2021 Jan;
9(1):9.
PMID: 33514438
Background: Prostate cancer tissues are inherently heterogeneous, which presents a challenge for metabolic profiling using traditional bulk analysis methods that produce an averaged profile. The aim of this study was...
9.
Simultaneous Detection of Zinc and Its Pathway Metabolites Using MALDI MS Imaging of Prostate Tissue
Andersen M, Krossa S, Hoiem T, Buchholz R, Claes B, Balluff B, et al.
Anal Chem
. 2020 Jan;
92(4):3171-3179.
PMID: 31944670
Levels of zinc, along with its mechanistically related metabolites citrate and aspartate, are widely reported as reduced in prostate cancer compared to healthy tissue and are therefore pointed out as...
10.
Bartels A, Gottert S, Desel C, Schafer M, Krossa S, Scheidig A, et al.
Cell Physiol Biochem
. 2019 Apr;
52(4):850-868.
PMID: 30958660
Background/aims: Endoplasmic reticulum (ER)-resident proteins with a C-terminal KDEL ERretention sequence are captured in the Golgi apparatus by KDEL receptors (KDELRs). The binding of such proteins to these receptors induces...