Astrid Deschenes
Overview
Explore the profile of Astrid Deschenes including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
16
Citations
777
Followers
0
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Recent Articles
1.
Tonelli C, Deschenes A, Gaeth V, Jensen A, Vithlani N, Yao M, et al.
bioRxiv
. 2024 Oct;
PMID: 39463990
Statement Of Significance: Mutant KRAS-expressing pancreatic intraepithelial neoplasias (PanINs), the precursor lesions of PDA, are prevalent in the average healthy adult but rarely advance to invasive carcinoma. Here, we discovered...
2.
Tonelli C, Yordanov G, Hao Y, Deschenes A, Hinds J, Belleau P, et al.
Gut
. 2024 Jan;
73(6):941-954.
PMID: 38262672
Objective: The optimal therapeutic response in cancer patients is highly dependent upon the differentiation state of their tumours. Pancreatic ductal adenocarcinoma (PDA) is a lethal cancer that harbours distinct phenotypic...
3.
Belleau P, Deschenes A, Chambwe N, Tuveson D, Krasnitz A
Cancer Res
. 2023 Jan;
83(2):347.
PMID: 36594871
No abstract available.
4.
Belleau P, Deschenes A, Chambwe N, Tuveson D, Krasnitz A
Cancer Res
. 2022 Nov;
83(1):49-58.
PMID: 36351074
Significance: The development of a computational approach that enables accurate and robust ancestry inference from cancer-derived molecular profiles without matching cancer-free data provides a valuable methodology for genetic ancestry-oriented cancer...
5.
Maurice C, Dalvai M, Lambrot R, Deschenes A, Scott-Boyer M, McGraw S, et al.
Epigenomes
. 2021 Dec;
5(2).
PMID: 34968297
Due to the grasshopper effect, the Arctic food chain in Canada is contaminated with persistent organic pollutants (POPs) of industrial origin, including polychlorinated biphenyls and organochlorine pesticides. Exposure to POPs...
6.
Miyabayashi K, Baker L, Deschenes A, Traub B, Caligiuri G, Plenker D, et al.
Cancer Discov
. 2020 Jul;
10(10):1566-1589.
PMID: 32703770
Pancreatic ductal adenocarcinoma (PDAC) is the most lethal common malignancy, with little improvement in patient outcomes over the past decades. Recently, subtypes of pancreatic cancer with different prognoses have been...
7.
Oni T, Biffi G, Baker L, Hao Y, Tonelli C, Somerville T, et al.
J Exp Med
. 2020 Jul;
217(9).
PMID: 32633781
Pancreatic ductal adenocarcinoma (PDAC) has a dismal prognosis, and new therapies are needed. Altered metabolism is a cancer vulnerability, and several metabolic pathways have been shown to promote PDAC. However,...
8.
Froeling F, Swamynathan M, Deschenes A, Chio I, Brosnan E, Yao M, et al.
Clin Cancer Res
. 2019 Sep;
25(23):7162-7174.
PMID: 31527169
Purpose: Napabucasin (2-acetylfuro-1,4-naphthoquinone or BBI-608) is a small molecule currently being clinically evaluated in various cancer types. It has mostly been recognized for its ability to inhibit STAT3 signaling. However,...
9.
Tiriac H, Belleau P, Engle D, Plenker D, Deschenes A, Somerville T, et al.
Cancer Discov
. 2018 Jun;
8(9):1112-1129.
PMID: 29853643
Pancreatic cancer is the most lethal common solid malignancy. Systemic therapies are often ineffective, and predictive biomarkers to guide treatment are urgently needed. We generated a pancreatic cancer patient-derived organoid...
10.
Belleau P, Deschenes A, Scott-Boyer M, Lambrot R, Dalvai M, Kimmins S, et al.
Nucleic Acids Res
. 2018 May;
46(14):7466.
PMID: 29788315
No abstract available.