Aoife Cannon
Overview
Explore the profile of Aoife Cannon including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
153
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Recent Articles
1.
Cannon A, Maher S, Lynam-Lennon N
Methods Mol Biol
. 2023 May;
2645:139-152.
PMID: 37202615
Radiation therapy is a cornerstone of cancer treatment worldwide. Unfortunately, in many cases, it does not control tumor growth, and many tumors display treatment resistance. The molecular pathways leading to...
2.
Alhusaini A, Cannon A, Maher S, Reynolds J, Lynam-Lennon N
Biomedicines
. 2021 Aug;
9(8).
PMID: 34440228
Gastrointestinal (GI) malignancies are a major global health burden, with high mortality rates. The identification of novel therapeutic strategies is crucial to improve treatment and survival of patients. The poly...
3.
OBrien R, Cannon A, Reynolds J, Lysaght J, Lynam-Lennon N
Cancers (Basel)
. 2021 Apr;
13(6).
PMID: 33802004
In recent years, our knowledge of the complement system beyond innate immunity has progressed significantly. A modern understanding is that the complement system has a multifaceted role in malignancy, impacting...
4.
Heeran A, Dunne M, Morrissey M, Buckley C, Clarke N, Cannon A, et al.
Cancers (Basel)
. 2021 Feb;
13(3).
PMID: 33540635
Locally advanced rectal cancer is treated with neoadjuvant-chemoradiotherapy; however, only ~22% of patients achieve a complete response, and resistance mechanisms are poorly understood. The role of inflammation and immune cell...
5.
Cannon A, Clarke N, MacCarthy F, Dunne C, Kevans D, Mahmud N, et al.
JGH Open
. 2020 Dec;
4(6):1191-1198.
PMID: 33319055
Background And Aim: Ulcerative colitis (UC) is an autoimmune disease characterized by inflammation in the gastrointestinal tract. The severity of UC is higher in nonsmokers than smokers; however, the biological...
6.
Chan K, Frankish N, Zhang T, Ece A, Cannon A, OSullivan J, et al.
J Pharm Pharmacol
. 2020 Apr;
72(7):927-937.
PMID: 32301120
Objectives: PH46A (1) demonstrates significant anti-inflammatory activity in phenotypic models but its mechanism and site of action have been elusive. Current study focused on the bioactivity of PH46 (2) and...
7.
Cannon A, Nally F, Collins A, Fay R, Lyons S
Int J Prison Health
. 2019 Jun;
15(2):105-113.
PMID: 31172855
Purpose: Many studies show that incarcerated populations have higher rates of problem drug use than the general population. The purpose of this paper is to analyse trends in addiction treatment...
8.
Mongan A, Lynam-Lennon N, Doyle S, Casey R, Carr E, Cannon A, et al.
Int J Med Sci
. 2019 Jun;
16(4):519-528.
PMID: 31171903
Oesophageal adenocarcinoma (OAC) is an exemplar model of obesity-associated cancer. Response to neoadjuvant chemoradiotherapy (NA CRT) is a clinical challenge. We examined if visceral adipose tissue and obesity status alter...
9.
Buckley A, Dunne M, Lynam-Lennon N, Kennedy S, Cannon A, Reynolds A, et al.
Cancer Lett
. 2019 Jan;
447:115-129.
PMID: 30664962
Oesophageal adenocarcinoma (OAC) is an aggressive disease with 5-year survival rates of <20%. Only 20-30% OAC patients show a beneficial response to neoadjuvant therapy. Altered mitochondrial function is linked with...
10.
Conroy M, Galvin K, Doyle S, Kavanagh M, Mongan A, Cannon A, et al.
Inflammation
. 2016 Jul;
39(5):1729-36.
PMID: 27423204
In the midst of a worsening obesity epidemic, the incidence of obesity-associated morbidities, including cancer, diabetes, cardiac and liver disease is increasing. Insights into mechanisms underlying pathological obesity-associated inflammation are...