Antonella Brizzi
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Explore the profile of Antonella Brizzi including associated specialties, affiliations and a list of published articles.
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52
Citations
309
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Recent Articles
1.
Poggialini F, Governa P, Vagaggini C, Maramai S, Lamponi S, Mugnaini C, et al.
Eur J Pharm Sci
. 2025 Mar;
:107066.
PMID: 40064401
The possibility to control the effects of drugs in time and space represents an ideal condition for developing safer and more personalized therapies against different disorders. In this context, photopharmacology...
2.
Maramai S, Mugnaini C, Paolino M, Moriello A, De Petrocellis L, Corelli F, et al.
Molecules
. 2025 Feb;
30(3).
PMID: 39942824
Due to its central role in pain, inflammation, and related disorders, the Transient Receptor Potential (TPR) Vanilloid Type-1 (TRPV1) ion channel represents an attractive target for the development of novel...
3.
Pessina F, Casini I, Gamberucci A, Carullo G, Signorini C, Brizzi A, et al.
Int J Mol Sci
. 2024 Nov;
25(21).
PMID: 39519187
Free fatty acid receptor 1 (FFAR1) has emerged as the most targeted isoform of the free fatty acid receptors because of its involvement in the modulation of energy balance and...
4.
Mugnaini C, Brizzi A, Paolino M, Scarselli E, Castelli R, De Candia M, et al.
ACS Chem Neurosci
. 2024 Feb;
15(5):955-971.
PMID: 38372253
Alzheimer's disease (AD) is a neurodegenerative form of dementia characterized by the loss of synapses and a progressive decline in cognitive abilities. Among current treatments for AD, acetylcholinesterase (AChE) inhibitors...
5.
Paolino M, De Candia M, Purgatorio R, Catto M, Saletti M, Tondo A, et al.
Molecules
. 2023 Aug;
28(15).
PMID: 37570828
The multitarget therapeutic strategy, as opposed to the more traditional 'one disease-one target-one drug', may hold promise in treating multifactorial neurodegenerative syndromes, such as Alzheimer's disease (AD) and related dementias....
6.
Carullo G, Mazzotta S, Ceramella J, Iacopetta D, Ramunno A, Rosano C, et al.
Arch Pharm (Weinheim)
. 2023 Jul;
356(10):e2300270.
PMID: 37452410
Topoisomerases are ubiquitous enzymes in the human body, particularly involved in cancer development and progression. Topoisomerase I (topoI) performs DNA relaxation reactions by "controlled rotation" rather than by "strand passage."...
7.
Mugnaini C, Kostrzewa M, Casini M, Kumar P, Catallo V, Allara M, et al.
Molecules
. 2023 Jul;
28(13).
PMID: 37446625
Selective ligands of the CB2 receptor are receiving considerable attention due to their potential as therapeutic agents for a variety of diseases. Recently, 7-hydroxy-5-oxopyrazolo[4,3-]pyridine-6-carboxamide derivatives were shown to act at...
8.
Romeo I, Brizzi A, Pessina F, Ambrosio F, Aiello F, Belardo C, et al.
J Med Chem
. 2023 May;
66(10):6994-7015.
PMID: 37192374
We describe an -guided rational drug design and the synthesis of the suggested ligands, aimed at improving the TRPV1-ligand binding properties and the potency of -(4-hydroxy-3-methoxybenzyl)-4-(thiophen-2-yl) butanamide , a previously...
9.
Sannio F, Brizzi A, Del Prete R, Avigliano M, Simone T, Pagli C, et al.
Antibiotics (Basel)
. 2022 Dec;
11(12).
PMID: 36551489
The diffusion of antibiotic-resistant, Gram-negative, opportunistic pathogens, an increasingly important global public health issue, causes a significant socioeconomic burden. isolates, despite causing a lower number of infections than Enterobacterales, often...
10.
Brizzi A, Maramai S, Aiello F, Baratto M, Corelli F, Mugnaini C, et al.
Int J Mol Sci
. 2022 Nov;
23(21).
PMID: 36362364
α-Lipoic acid is a sulfur-containing nutrient endowed with pleiotropic actions and a safe biological profile selected to replace the unsaturated alkyl acid of capsaicin with the aim of obtaining lipoic...