Anthony N Hollenberg
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Explore the profile of Anthony N Hollenberg including associated specialties, affiliations and a list of published articles.
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95
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3066
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Recent Articles
1.
Ritter M, Amano I, Hollenberg A
Endocrinology
. 2024 Dec;
166(2).
PMID: 39679543
Thyroid hormone (TH) is essential throughout life. Its actions are mediated primarily by the thyroid hormone receptor (THR), which is a nuclear receptor. Classically, the THRs act as inducible transcription...
2.
Xu X, Mendoza A, Krumm C, Su S, Acuna M, Bare C, et al.
Sci Signal
. 2024 Dec;
17(865):eadk7971.
PMID: 39626011
Activation of thermogenic brown adipose tissue (BAT) and inducible beige adipose tissue (BeAT) is triggered by environmental or metabolic stimuli, including cold ambient temperatures and nutrient stress. Thioesterase superfamily member...
3.
Undeutsch H, Posabella A, Alber A, Bawa P, Villacorta-Martin C, Wang F, et al.
Stem Cell Reports
. 2024 Nov;
19(12):1690-1705.
PMID: 39515316
The production of mature functioning thyroid follicular cells (TFCs) from human induced pluripotent stem cells (iPSCs) is critical for potential novel therapeutic approaches to post-surgical and congenital hypothyroidism. To accomplish...
4.
Soares De Oliveira L, Kaserman J, Van Der Spek A, Lee N, Undeutsch H, Werder R, et al.
Mol Metab
. 2024 Oct;
90:102057.
PMID: 39481850
Objective: Thyroid hormone (TH) action is mediated by thyroid hormone receptor (THR) isoforms. While THRβ1 is likely the main isoform expressed in liver, its role in human hepatocytes is not...
5.
Hu Y, Soares De Oliveira L, Falize K, van Trotsenburg A, Fliers E, Kaserman J, et al.
Eur Thyroid J
. 2024 Sep;
13(5).
PMID: 39316725
Background: Mutations in TBL1X, part of the NCOR1/SMRT corepressor complex, were identified in patients with hereditary X-linked central congenital hypothyroidism and associated hearing loss. The role of TBL1X in thyroid...
6.
Ritter M, Amano I, Van Der Spek A, Gower A, Undeutsch H, Rodrigues V, et al.
Endocrinology
. 2024 Aug;
165(9).
PMID: 39106294
Nuclear receptor action is mediated in part by the nuclear receptor corepressor 1 (NCOR1) and the silencing mediator of retinoic acid and thyroid hormone receptor (SMRT). NCOR1 and SMRT regulate...
7.
Maddox S, Ponomareva O, Zaleski C, Chen M, Vella K, Hollenberg A, et al.
Mol Psychiatry
. 2024 Jul;
30(1):201-212.
PMID: 39039155
The amygdala is an established site for fear memory formation, and clinical studies suggest involvement of hormone signaling cascades in development of trauma-related disorders. While an association of thyroid hormone...
8.
Thyroid hormone-regulated chromatin landscape and transcriptional sensitivity of the pituitary gland
Cho Y, Fu Y, Huang C, Wu X, Ng L, Kelley K, et al.
Commun Biol
. 2023 Dec;
6(1):1253.
PMID: 38081939
Thyroid hormone (3,5,3'-triiodothyronine, T3) is a key regulator of pituitary gland function. The response to T3 is thought to hinge crucially on interactions of nuclear T3 receptors with enhancers but...
9.
Burris T, de Vera I, Cote I, Flaveny C, Wanninayake U, Chatterjee A, et al.
Pharmacol Rev
. 2023 Aug;
75(6):1233-1318.
PMID: 37586884
The NR superfamily comprises 48 transcription factors in humans that control a plethora of gene network programs involved in a wide range of physiologic processes. This review will summarize and...
10.
Hu Y, Bruinstroop E, Hollenberg A, Fliers E, Boelen A
J Mol Endocrinol
. 2023 May;
71(1).
PMID: 37256579
WD40 repeat-containing proteins play a key role in many cellular functions including signal transduction, protein degradation, and apoptosis. The WD40 domain is highly conserved, and its typical structure is a...