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Anne C Cotleur

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Articles 19
Citations 1598
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Recent Articles
1.
Rorex C, Cardona S, Church K, Rodriguez D, Vanegas D, Saldivar R, et al.
Int J Mol Sci . 2025 Feb; 26(3). PMID: 39940901
Diabetic retinopathy (DR) causes vision loss due to sustained inflammation and vascular damage. The vascular damage is evident by fibrinogen leakage, angiogenesis, and hypoxia. Neuronal regulation of microglia via the...
2.
Church K, Rodriguez D, Mendiola A, Vanegas D, Gutierrez I, Tamayo I, et al.
Front Immunol . 2023 Apr; 14:1130735. PMID: 37033925
Diabetic retinopathy, a microvascular disease characterized by irreparable vascular damage, neurodegeneration and neuroinflammation, is a leading complication of diabetes mellitus. There is no cure for DR, and medical interventions marginally...
3.
Gyoneva S, Hosur R, Gosselin D, Zhang B, Ouyang Z, Cotleur A, et al.
Life Sci Alliance . 2019 Dec; 2(6). PMID: 31792059
CX3CR1, one of the highest expressed genes in microglia in mice and humans, is implicated in numerous microglial functions. However, the molecular mechanisms underlying signaling are not well understood. Here,...
4.
Shimizu F, Schaller K, Owens G, Cotleur A, Kellner D, Takeshita Y, et al.
Sci Transl Med . 2017 Jul; 9(397). PMID: 28679661
Neuromyelitis optica (NMO) is an inflammatory disorder mediated by antibodies to aquaporin-4 (AQP4) with prominent blood-brain barrier (BBB) breakdown in the acute phase of the disease. Anti-AQP4 antibodies are produced...
5.
Saederup N, Cardona A, Croft K, Mizutani M, Cotleur A, Tsou C, et al.
PLoS One . 2017 Apr; 12(4):e0176931. PMID: 28448577
[This corrects the article DOI: 10.1371/journal.pone.0013693.].
6.
Takeshita Y, Obermeier B, Cotleur A, Spampinato S, Shimizu F, Yamamoto E, et al.
Neurol Neuroimmunol Neuroinflamm . 2016 Dec; 4(1):e311. PMID: 28018943
Objective: To address the hypothesis that physiologic interactions between astrocytes and endothelial cells (EC) at the blood-brain barrier (BBB) are afflicted by pathogenic inflammatory signaling when astrocytes are exposed to...
7.
Liu L, Spangler L, Prager B, Benson B, Hu B, Shi S, et al.
Neurol Neuroimmunol Neuroinflamm . 2015 Dec; 2(6):e174. PMID: 26668819
Background: Residual CXCR2 expression on CNS cells in Cxcr2 (+/-) →Cxcr2 (-/-) chimeric animals slowed remyelination after both experimental autoimmune encephalomyelitis and cuprizone-induced demyelination. Methods: We generated Cxcr2 (fl/-) :PLPCre-ER(T)...
8.
Jay T, Miller C, Cheng P, Graham L, Bemiller S, Broihier M, et al.
J Exp Med . 2015 Mar; 212(3):287-95. PMID: 25732305
Variants in triggering receptor expressed on myeloid cells 2 (TREM2) confer high risk for Alzheimer's disease (AD) and other neurodegenerative diseases. However, the cell types and mechanisms underlying TREM2's involvement...
9.
Yamasaki R, Lu H, Butovsky O, Ohno N, Rietsch A, Cialic R, et al.
J Exp Med . 2014 Jul; 211(8):1533-49. PMID: 25002752
In the human disorder multiple sclerosis (MS) and in the model experimental autoimmune encephalomyelitis (EAE), macrophages predominate in demyelinated areas and their numbers correlate to tissue damage. Macrophages may be...
10.
Liu L, Li M, Spangler L, Spear C, Veenstra M, Darnall L, et al.
Genesis . 2013 May; 51(8):587-95. PMID: 23650205
Type 2 CXC chemokine receptor CXCR2 plays roles in development, tumorigenesis, and inflammation. CXCR2 also promotes demyelination and decreases remyelination by actions toward hematopoietic cells and nonhematopoietic cells. Germline CXCR2...