Anna K Puszko
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Explore the profile of Anna K Puszko including associated specialties, affiliations and a list of published articles.
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15
Citations
94
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Recent Articles
1.
Puszko A, Batista F, Ejjoummany A, Bouillon A, Maurel M, Adler P, et al.
ChemMedChem
. 2025 Jan;
:e202400924.
PMID: 39832214
After more than 15 years of decline, the Malaria epidemy has increased again since 2017, reinforcing the need to identify drug candidates active on new targets involved in at least...
2.
Grempka A, Dziubak D, Puszko A, Bachurska-Szpala P, Ivanov M, Vilarinho P, et al.
ACS Appl Mater Interfaces
. 2024 Jun;
16(24):31817-31825.
PMID: 38848259
We have designed and synthesized a helical cysteamine-terminated oligourea foldamer composed of ten urea residues featuring side carboxyl and amine groups. The carboxyl group is located in proximity to the...
3.
Legru A, Batista F, Puszko A, Bouillon A, Maurel M, Martinez M, et al.
Eur J Med Chem
. 2024 Mar;
269:116308.
PMID: 38503166
Plasmodium multi-resistance, including against artemisinin, seriously threatens malaria treatment and control. Hence, new drugs are urgently needed, ideally targeting different parasitic stages, which are not yet targeted by current drugs....
4.
Puszko A, Sosnowski P, Hermine O, Hopfgartner G, Lepelletier Y, Misicka A
Bioorg Med Chem
. 2023 Sep;
94:117482.
PMID: 37774449
Neuropilin-1 (NRP-1) is a major co-receptor of vascular endothelial growth factor receptor-2 (VEGFR-2). It may also stimulate tumour growth and metastasis independently of VEGF-A. These functions make VEGF-A/NRP-1 complex formation...
5.
Dumond A, Brachet E, Durivault J, Vial V, Puszko A, Lepelletier Y, et al.
J Exp Clin Cancer Res
. 2021 Jan;
40(1):33.
PMID: 33461580
Background: Despite the improvement of relapse-free survival mediated by anti-angiogenic drugs like sunitinib (Sutent®), or by combinations of anti-angiogenic drugs with immunotherapy, metastatic clear cell Renal Cell Carcinoma (mccRCC) remain...
6.
Puszko A, Sosnowski P, Rignault-Bricard R, Hermine O, Hopfgartner G, Pulka-Ziach K, et al.
Int J Mol Sci
. 2020 Dec;
22(1).
PMID: 33374715
Neuropilin-1 (NRP-1), the major co-receptor of vascular endothelial growth factor receptor-2 (VEGFR-2), may also independently act with VEGF-A to stimulate tumour growth and metastasis. Therefore, there is great interest in...
7.
Puszko A, Sosnowski P, Raynaud F, Hermine O, Hopfgartner G, Lepelletier Y, et al.
Biomolecules
. 2020 Mar;
10(3).
PMID: 32183142
The structure-activity relationship of branched H-Lys(Arg)-Dab-Dhp-Arg-OH sequence analogues, modified with Cys-Asp or Cys at N-terminal amino acids (Lys, Arg), in VEGF-A/Neuropilin-1 complex inhibition is presented. The addition of Cys residue...
8.
Puszko A, Sosnowski P, Pulka-Ziach K, Hermine O, Hopfgartner G, Lepelletier Y, et al.
Bioorg Med Chem Lett
. 2019 Jul;
29(17):2493-2497.
PMID: 31326342
NRP-1 is an important co-receptor of vascular endothelial growth factor receptor-2 (VEGFR-2). Many reports suggested that NRP-1 might also serve as a separate receptor for VEGF-A causing stimulation of tumour...
9.
Fedorczyk B, Lipinski P, Puszko A, Tymecka D, Wilenska B, Dudka W, et al.
Molecules
. 2019 May;
24(9).
PMID: 31064153
Inhibiting the interaction of neuropilin-1 (NRP-1) with vascular endothelial growth factor (VEGF) has become an interesting mechanism for potential anticancer therapies. In our previous works, we have obtained several submicromolar...
10.
Puszko A, Sosnowski P, Tymecka D, Raynaud F, Hermine O, Lepelletier Y, et al.
Medchemcomm
. 2019 Mar;
10(2):332-340.
PMID: 30881620
Many reports have suggested that NRP-1 acts as a co-receptor for VEGF-A and boosts tumour growth and metastasis. This NRP-1, due to its important role in tumour progression, triggered interest...