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Aleksandra Misicka

Explore the profile of Aleksandra Misicka including associated specialties, affiliations and a list of published articles. Areas
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Articles 82
Citations 467
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Recent Articles
1.
Tymecka D, Redkiewicz P, Lipinski P, Misicka A
Amino Acids . 2024 Aug; 56(1):49. PMID: 39181965
Inhibitors of the interaction between Neuropilin-1 (NRP-1) and Vascular Endothelial Growth Factor-A (VEGF-A) hold significant promise as therapeutic and diagnostic agents directed against cancers overexpressing NRP-1. In our efforts in...
2.
Rozanowska M, Szczupaj G, Nowakowski M, Rajagopal P, Lipinski P, Matalinska J, et al.
Amino Acids . 2024 Mar; 56(1):18. PMID: 38427104
A series of 10 cyclic, biaryl analogs of enkephalin, with Tyr or Phe residues at positions 1 and 4, were synthesized according to the Miyaura borylation and Suzuki coupling methodology....
3.
Witoszka K, Matalinska J, Misicka A, Lipinski P
ChemMedChem . 2023 Oct; 18(23):e202300315. PMID: 37821725
The NK1 receptor (NK1R) is a molecular target for both approved and experimental drugs intended for a variety of conditions, including emesis, pain, and cancers. While contemplating modifications to the...
4.
Puszko A, Sosnowski P, Hermine O, Hopfgartner G, Lepelletier Y, Misicka A
Bioorg Med Chem . 2023 Sep; 94:117482. PMID: 37774449
Neuropilin-1 (NRP-1) is a major co-receptor of vascular endothelial growth factor receptor-2 (VEGFR-2). It may also stimulate tumour growth and metastasis independently of VEGF-A. These functions make VEGF-A/NRP-1 complex formation...
5.
Redkiewicz P, Dyniewicz J, Witkowska E, Misicka A, Lipinski P
J Pept Sci . 2023 Mar; 29(9):e3487. PMID: 36898693
The treatment of hard-to-heal chronic wounds is still a major medical problem and an economic and social burden. In this work, we examine the proregenerative potential of two peptides, G11...
6.
Kosson P, Dyniewicz J, Lipinski P, Matalinska J, Misicka A, Bojarski A, et al.
Pharmacol Rep . 2023 Feb; 75(2):465-473. PMID: 36840824
Background: G protein-coupled receptors (GPCRs) transduce external stimuli into the cell by G proteins via an allosteric mechanism. Agonist binding to the receptor stimulates GDP/GTP exchange within the heterotrimeric G...
7.
Maslowska K, Redkiewicz P, Halik P, Witkowska E, Tymecka D, Walczak R, et al.
Biomedicines . 2023 Feb; 11(2). PMID: 36831099
Pathological angiogenesis, resulting from an imbalance between anti- and pro-angiogenic factors, plays a pivotal role in tumor growth, development and metastasis. The inhibition of the angiogenesis process by the VEGF/VEGFR-2/NRP-1...
8.
Halik P, Kozminski P, Matalinska J, Lipinski P, Misicka A, Gniazdowska E
Pharmaceutics . 2022 Mar; 14(3). PMID: 35335981
Currently, the search for promising NK1R-positive tumor-targeting radiopharmaceuticals based on the structure of small molecular antagonists of neurokinin-1 receptor can be observed. Following this trend, we continued our evaluation of...
9.
Naliwajski M, Wilenska B, Misicka A, Pietrosiuk A, Syklowska-Baranek K
Cells . 2022 Mar; 11(6). PMID: 35326382
To cope with environmental harmful conditions, plant cells developed adaptive strategy that involves production of a wide variety of complex secondary metabolites. The spectrum and quantity of biosynthesized compounds in...
10.
Matalinska J, Kosinska K, Halik P, Kozminski P, Lipinski P, Gniazdowska E, et al.
Int J Mol Sci . 2022 Feb; 23(3). PMID: 35163139
Locoregionally administered, NK1 receptor (NK1R) targeted radionuclide therapy is a promising strategy for the treatment of glioblastoma multiforme. So far, the radiopharmaceuticals used in this approach have been based on...