Anna Alcaide
Overview
Explore the profile of Anna Alcaide including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
9
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Recent Articles
1.
Stockwell S, Scott D, Fischer G, Guarino E, Rooney T, Feng T, et al.
J Med Chem
. 2024 Aug;
67(17):15521-15536.
PMID: 39190548
Aurora A kinase, a cell division regulator, is frequently overexpressed in various cancers, provoking genome instability and resistance to antimitotic chemotherapy. Localization and enzymatic activity of Aurora A are regulated...
2.
Buschbom-Helmke S, Wang P, Alcaide A, Miguez-Cabello F, Carta M, Viotti J, et al.
J Med Chem
. 2024 Aug;
67(16):14524-14542.
PMID: 39133077
Twenty-one simplified analogues of the natural product domoic acid were designed, synthesized, and then characterized at homomeric kainic acid (KA) receptors (GluK1-3,5). displays a high affinity for homomeric GluK5 receptors...
3.
Borras-Tuduri R, Alcaide A, Aspeslag S, Usero L, Serra C, Roura-Mir C, et al.
ChemMedChem
. 2021 Apr;
16(16):2491-2496.
PMID: 33821540
Natural Killer T (NKT) cells play an important role in the immune response and can be activated by glycolipids presented by CD1d protein. We present MCS-0208, an unprecedented arylthioether-phytoceramide able...
4.
Poulie C, Alcaide A, Krell-Jorgensen M, Larsen Y, Astier E, Bjorn-Yoshimoto W, et al.
ACS Chem Neurosci
. 2019 May;
10(6):2989-3007.
PMID: 31124660
Development of pharmacological tools for the ionotropic glutamate receptors (iGluRs) is imperative for the study and understanding of the role and function of these receptors in the central nervous system....
5.
Alcaide A, Trapero A, Perez Y, Llebaria A
Org Biomol Chem
. 2015 Apr;
13(20):5690-7.
PMID: 25895752
A new type of galactose mimetics has been synthesized following a straightforward synthetic approach based on cyclohexene olefin aziridination reactions directed by hydroxyl substituents. These enantiomerically pure galacto-configured N-aminoaziridines are...
6.
Alcaide A, Llebaria A
J Org Chem
. 2014 Mar;
79(7):2993-3029.
PMID: 24641332
A library of sphingolipid analogues is designed and tested as inhibitors against mammalian and fungal sphingolipid enzymes. The synthesis of sphingolipid analogues is based on the nucleophilic ring-opening reactions of...