Christian B M Poulie
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Explore the profile of Christian B M Poulie including associated specialties, affiliations and a list of published articles.
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21
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119
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Recent Articles
1.
Herth M, Hvass L, Poulie C, Muller M, Garcia-Vazquez R, Gustavsson T, et al.
J Med Chem
. 2025 Feb;
68(4):4410-4425.
PMID: 39963966
Pretargeted radioimmunoimaging has been shown to enhance tumor-to-background ratios by up to 125-fold at early time points, leading to more efficient and less toxic radionuclide therapies, particularly with shorter half-lives...
2.
Chan C, Pottie E, Simon I, Rossebo A, Herth M, Harpsoe K, et al.
ACS Chem Neurosci
. 2025 Jan;
16(3):439-451.
PMID: 39836645
The serotonin 7 receptor (5-HTR) regulates various processes in the central nervous system, including mood, learning, and circadian rhythm control, among others. Receptor activation can lead to activation of the...
3.
Poulie C, Muller M, Bom Pedersen N, Martin M, Muhlbauer V, Mattiussi S, et al.
Chemistry
. 2024 Oct;
30(67):e202403446.
PMID: 39412494
Organometallics can be used as precursors for electrophilic At-statinations. In this report, we compared the potential of aryl trimethylsilanes, -germanes, or -stannanes to be used as precursors to At-label highly...
4.
Poulie C, Piel M, Neumaier B, Ross T, Herth M
Front Nucl Med
. 2024 Oct;
3:1336481.
PMID: 39355036
No abstract available.
5.
Bohrmann L, Poulie C, Rodriguez-Rodriguez C, Karagiozov S, Saatchi K, Herth M, et al.
PLoS One
. 2024 Apr;
19(4):e0300466.
PMID: 38626058
Pretargeting, which is the separation of target accumulation and the administration of a secondary imaging agent into two sequential steps, offers the potential to improve image contrast and reduce radiation...
6.
El Fakiri M, Ayada N, Muller M, Hvass L, Gamzov T, Clausen A, et al.
J Nucl Med
. 2024 Feb;
65(4):593-599.
PMID: 38423784
The application of prostate-specific membrane antigen (PSMA)-targeted α-therapy is a promising alternative to β-particle-based treatments. At is among the potential α-emitters that are favorable for this concept. Herein, At-based PSMA...
7.
Poulie C, Shalgunov V, Elvas F, Van Rymenant Y, Moon E, Battisti U, et al.
Eur J Med Chem
. 2023 Oct;
262:115862.
PMID: 37883899
Small-molecular fibroblast activation protein inhibitor (FAPI)-based tracer have been shown to be promising Positron Emission Tomography (PET) Ga-labeled radiopharmaceuticals to image a variety of tumors including pancreatic, breast, and colorectal...
8.
Poulie C, Chan C, Parka A, Lettorp M, Vos J, Raaschou A, et al.
ACS Pharmacol Transl Sci
. 2023 Oct;
6(10):1492-1507.
PMID: 37854625
Quality of life is often reduced in patients with sleep-wake disorders. Insomnia is commonly treated with benzodiazepines, despite their well-known side effects. Pellotine (), a alkaloid, has been reported to...
9.
Pottie E, Poulie C, Simon I, Harpsoe K, DAndrea L, Komarov I, et al.
ACS Chem Neurosci
. 2023 Jul;
14(15):2727-2742.
PMID: 37474114
Serotonergic psychedelics are described to have activation of the serotonin 2A receptor (5-HT) as their main pharmacological action. Despite their relevance, the molecular mechanisms underlying the psychedelic effects induced by...
10.
Bidesi N, Shalgunov V, Battisti U, Hvass L, Jorgensen J, Poulie C, et al.
J Labelled Comp Radiopharm
. 2022 Dec;
66(1):22-30.
PMID: 36539610
Pretargeting imaging has gained a lot of prominence, due to its excellent bioorthogonality and improved imaging contrast compared to conventional imaging. A new iodo tetrazine (Tz) derivative has been synthesized...