Anja Jaeschke
Overview
Explore the profile of Anja Jaeschke including associated specialties, affiliations and a list of published articles.
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40
Citations
1028
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Recent Articles
1.
Turkson V, Haller A, Jaeschke A, Hui D
Arterioscler Thromb Vasc Biol
. 2024 Nov;
45(1):37-48.
PMID: 39508104
Background: apoER2 (apolipoprotein E receptor-2) is a transmembrane receptor in the low-density lipoprotein receptor (LDLR) family with unique tissue expression. A single-nucleotide polymorphism that encodes the R952Q sequence variant has...
2.
Haller A, Wolfkiel P, Jaeschke A, Hui D
Int J Mol Sci
. 2023 Nov;
24(22).
PMID: 38003345
Phospholipase A (PLA) enzymes influence inflammatory bowel disease in both positive and negative manners depending on the type of PLA that is expressed. This study explored the influence of the...
3.
Wolfkiel P, Haller A, Kirby J, Jaeschke A, Hui D
Am J Physiol Regul Integr Comp Physiol
. 2023 May;
325(1):R55-R68.
PMID: 37212552
This study explored the role of apoE receptor-2 (apoER2), a unique member of the LDL receptor family proteins with a restricted tissue expression profile, in modulating diet-induced obesity and diabetes....
4.
Alagarsamy J, Jaeschke A, Hui D
Int J Mol Sci
. 2022 Sep;
23(17).
PMID: 36077289
A preponderance of evidence obtained from genetically modified mice and human population studies reveals the association of apolipoprotein E (apoE) deficiency and polymorphisms with pathogenesis of numerous chronic diseases, including...
5.
Kidane Y, Hoffmann S, Jaeschke A, Beloiu M, Beierkuhnlein C
Sci Rep
. 2022 Feb;
12(1):1858.
PMID: 35115621
Climate change impacts the structure, functioning, and distribution of species and ecosystems. It will shift ecosystem boundaries, potentially affecting vulnerable ecosystems, such as tropical Africa's high mountain ecosystems, i.e., afroalpine...
6.
Igel E, Haller A, Wolfkiel P, Orr-Asman M, Jaeschke A, Hui D
J Biol Chem
. 2021 Aug;
297(3):101106.
PMID: 34425108
Polymorphisms in the apolipoprotein E (apoE) gene are risk factors for chronic inflammatory diseases including atherosclerosis. The gene product apoE is synthesized in many cell types and has both lipid...
7.
Jaeschke A, Hui D
Curr Opin Lipidol
. 2021 Jul;
32(5):301-307.
PMID: 34310383
Purpose Of Review: LDL receptor-related protein 1 (LRP1) is a multifunctional protein with endocytic and signal transduction properties due to its interaction with numerous extracellular ligands and intracellular proteins. This...
8.
Kuhls K, Moskalenko O, Sukiasyan A, Manukyan D, Melik-Andreasyan G, Atshemyan L, et al.
PLoS Negl Trop Dis
. 2021 Apr;
15(4):e0009288.
PMID: 33872307
Background: Visceral leishmaniasis (VL) is re-emerging in Armenia since 1999 with 167 cases recorded until 2019. The objectives of this study were (i) to determine for the first time the...
9.
Chinnarasu S, Alogaili F, Bove K, Jaeschke A, Hui D
J Biol Chem
. 2021 Feb;
296:100370.
PMID: 33548224
The LDL receptor-related protein 1 (LRP1) is a multifunctional transmembrane protein with endocytosis and signal transduction functions. Previous studies have shown that hepatic LRP1 deficiency exacerbates diet-induced steatohepatitis and insulin...
10.
Jaeschke A, Haller A, Cash J, Nam C, Igel E, Roebroek A, et al.
J Lipid Res
. 2021 Jan;
62:100012.
PMID: 33500241
The impairment of LDL receptor-related protein-1 (LRP1) in numerous cell types is associated with obesity, diabetes, and fatty liver disease. Here, we compared the metabolic phenotype of C57BL/6J wild-type and...