Angela Volorio
Overview
Explore the profile of Angela Volorio including associated specialties, affiliations and a list of published articles.
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10
Citations
588
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Recent Articles
1.
Boulay G, Broye L, Dong R, Iyer S, Sanalkumar R, Xing Y, et al.
Nat Commun
. 2024 Aug;
15(1):7460.
PMID: 39198430
EWS fusion oncoproteins underlie several human malignancies including Desmoplastic Small Round Cell Tumor (DSRCT), an aggressive cancer driven by EWS-WT1 fusion proteins. Here we combine chromatin occupancy and 3D profiles...
2.
Tak Y, Boulay G, Lee L, Iyer S, Perry N, Schultz H, et al.
Cell Genom
. 2022 Aug;
2(4).
PMID: 35967079
Repeat elements can be dysregulated at a genome-wide scale in human diseases. For example, in Ewing sarcoma, hundreds of inert GGAA repeats can be converted into active enhancers when bound...
3.
Jerby-Arnon L, Neftel C, Shore M, Weisman H, Mathewson N, McBride M, et al.
Nat Med
. 2021 Jan;
27(2):289-300.
PMID: 33495604
Synovial sarcoma (SyS) is an aggressive neoplasm driven by the SS18-SSX fusion, and is characterized by low T cell infiltration. Here, we studied the cancer-immune interplay in SyS using an...
4.
Keskin T, Bakaric A, Waszyk P, Boulay G, Torsello M, Cornaz-Buros S, et al.
Cell Rep
. 2020 Apr;
31(2):107539.
PMID: 32294441
No abstract available.
5.
Keskin T, Bakaric A, Waszyk P, Boulay G, Torsello M, Cornaz-Buros S, et al.
Cell Rep
. 2020 Apr;
30(13):4567-4583.e5.
PMID: 32234488
Ewing sarcoma (EwS) is associated with poor prognosis despite current multimodal therapy. Targeting of EWS-FLI1, the fusion protein responsible for its pathogenesis, and its principal downstream targets has not yet...
6.
Yan C, Brunson D, Tang Q, Do D, Iftimia N, Moore J, et al.
Cell
. 2019 Apr;
177(7):1903-1914.e14.
PMID: 31031007
Xenograft cell transplantation into immunodeficient mice has become the gold standard for assessing pre-clinical efficacy of cancer drugs, yet direct visualization of single-cell phenotypes is difficult. Here, we report an...
7.
Boulay G, Volorio A, Iyer S, Broye L, Stamenkovic I, Riggi N, et al.
Genes Dev
. 2018 Jul;
32(15-16):1008-1019.
PMID: 30042132
Various types of repetitive sequences are dysregulated in cancer. In Ewing sarcoma, the oncogenic fusion protein EWS-FLI1 induces chromatin features typical of active enhancers at GGAA microsatellite repeats, but the...
8.
Boulay G, Sandoval G, Riggi N, Iyer S, Buisson R, Naigles B, et al.
Cell
. 2017 Aug;
171(1):163-178.e19.
PMID: 28844694
Alterations in transcriptional regulators can orchestrate oncogenic gene expression programs in cancer. Here, we show that the BRG1/BRM-associated factor (BAF) chromatin remodeling complex, which is mutated in over 20% of...
9.
Boulay G, Awad M, Riggi N, Archer T, Iyer S, Boonseng W, et al.
Cancer Discov
. 2017 Feb;
7(3):288-301.
PMID: 28213356
Medulloblastoma is the most frequent malignant pediatric brain tumor and is divided into at least four subgroups known as WNT, SHH, Group 3, and Group 4. Here, we characterized gene...
10.
Miles W, Lembo A, Volorio A, Brachtel E, Tian B, Sgroi D, et al.
Cancer Res
. 2016 Oct;
76(24):7231-7241.
PMID: 27758885
Alternative polyadenylation (APA) is a process that changes the posttranscriptional regulation and translation potential of mRNAs via addition or deletion of 3' untranslated region (3' UTR) sequences. To identify posttranscriptional-regulatory...