Ivan Stamenkovic
Overview
Explore the profile of Ivan Stamenkovic including associated specialties, affiliations and a list of published articles.
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Articles
69
Citations
7103
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Recent Articles
1.
Boulay G, Broye L, Dong R, Iyer S, Sanalkumar R, Xing Y, et al.
Nat Commun
. 2024 Aug;
15(1):7460.
PMID: 39198430
EWS fusion oncoproteins underlie several human malignancies including Desmoplastic Small Round Cell Tumor (DSRCT), an aggressive cancer driven by EWS-WT1 fusion proteins. Here we combine chromatin occupancy and 3D profiles...
2.
Sundaramoorthy S, Colombo D, Sanalkumar R, Broye L, Balmas Bourloud K, Boulay G, et al.
JCI Insight
. 2024 Aug;
9(14).
PMID: 39133652
The development of targeted therapies offers new hope for patients affected by incurable cancer. However, multiple challenges persist, notably in controlling tumor cell plasticity in patients with refractory and metastatic...
3.
Stamenkovic I, Mazzolai L
Swiss Med Wkly
. 2024 Jul;
154:3738.
PMID: 38980691
No abstract available.
4.
Bakaric A, Cironi L, Praz V, Sanalkumar R, Broye L, Favre-Bulle K, et al.
Cancers (Basel)
. 2024 Jan;
16(2).
PMID: 38275898
CIC-DUX4-rearranged sarcoma (CDS) is a rare and aggressive soft tissue tumor that occurs most frequently in young adults. The key oncogenic driver of this disease is the expression of the...
5.
Sanalkumar R, Dong R, Lee L, Xing Y, Iyer S, Letovanec I, et al.
Sci Adv
. 2023 Mar;
9(13):eabo3789.
PMID: 37000878
Cell fate transitions observed in embryonic development involve changes in three-dimensional genomic organization that provide proper lineage specification. Whether similar events occur within tumor cells and contribute to cancer evolution...
6.
Moller E, Praz V, Rajendran S, Dong R, Cauderay A, Xing Y, et al.
Nat Commun
. 2022 Apr;
13(1):2267.
PMID: 35477713
Oncogenic fusion proteins generated by chromosomal translocations play major roles in cancer. Among them, fusions between EWSR1 and transcription factors generate oncogenes with powerful chromatin regulatory activities, capable of establishing...
7.
ElMokh O, Matsumoto S, Biniecka P, Bellotti A, Schaeuble K, Piacente F, et al.
Cell Death Dis
. 2022 Apr;
13(4):320.
PMID: 35396381
Most cancer cells have high need for nicotinamide adenine dinucleotide (NAD) to sustain their survival. This led to the development of inhibitors of nicotinamide (NAM) phosphoribosyltransferase (NAMPT), the rate-limiting NAD...
8.
Katakam S, Anand S, Martin P, Riggi N, Stamenkovic I
Life Sci Alliance
. 2022 Jan;
5(3).
PMID: 34983824
Malignant tumors commonly display necrosis, which invariably triggers an inflammatory response that supports tumor growth. However, the effect on tumor cells of necrotic debris, or damage-associated molecular patterns (DAMPs) released...
9.
Keskin T, Rucci B, Cornaz-Buros S, Martin P, Fusco C, Broye L, et al.
Sci Adv
. 2021 Jul;
7(27).
PMID: 34215585
Targeting of the most aggressive tumor cell subpopulations is key for effective management of most solid malignancies. However, the metastable nature of tumor heterogeneity, which allows cells to transition between...
10.
Riggi N, Suva M, Stamenkovic I
N Engl J Med
. 2021 Apr;
384(15):1477-1478.
PMID: 33852794
No abstract available.