Angel Cores
Overview
Explore the profile of Angel Cores including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
16
Citations
148
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0
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Recent Articles
1.
Duarte P, Sanchez-Porro F, Crisman E, Cores A, Jimenez I, Cuadrado A, et al.
J Med Chem
. 2025 Jan;
68(3):3495-3517.
PMID: 39818855
Parkinson's disease (PD), the second most common neurodegenerative disorder, affects around 10 million people worldwide. It is a multifactorial disease marked by dopaminergic neuron loss with oxidative stress (OS) and...
2.
Cores A, Carmona-Zafra N, Clerigue J, Villacampa M, Menendez J
Antioxidants (Basel)
. 2023 Jul;
12(7).
PMID: 37508002
Quinones can in principle be viewed as a double-edged sword in the treatment of neurodegenerative diseases, since they are often cytoprotective but can also be cytotoxic due to covalent and...
3.
Uliassi E, Bergamini C, Rizzardi N, Naldi M, Cores A, Bartolini M, et al.
Bioorg Med Chem
. 2023 Jul;
91:117419.
PMID: 37487339
Multi-target drug discovery is one of the most active fields in the search for new drugs against Alzheimer's disease (AD). This is because the complexity of AD pathological network might...
4.
Staderini M, Vanni S, Colini Baldeschi A, Giachin G, Zattoni M, Celauro L, et al.
Eur J Med Chem
. 2022 Nov;
245(Pt 1):114923.
PMID: 36423450
Prion diseases are characterized by the self-assembly of pathogenic misfolded scrapie isoforms (PrP) of the cellular prion protein (PrP). In an effort to achieve a theranostic profile, symmetrical bifunctional carbazole...
5.
Cores A, Clerigue J, Orocio-Rodriguez E, Menendez J
Pharmaceuticals (Basel)
. 2022 Aug;
15(8).
PMID: 36015157
Multicomponent reactions 9i.e., those that engage three or more starting materials to form a product that contains significant fragments of all of them), have been widely employed in the construction...
6.
Gonzalez-Ruiz V, Cores A, Caja M, Sridharan V, Villacampa M, Martin M, et al.
Biosensors (Basel)
. 2022 Mar;
12(3).
PMID: 35323445
The environmental presence of anions of natural origin or anthropogenic origin is gradually increasing. As a tool to tackle this problem, carbazole derivatives are an attractive gateway to the development...
7.
Cores A, Michalska P, Perez J, Crisman E, Gomez C, Villacampa M, et al.
Antioxidants (Basel)
. 2022 Jan;
11(1).
PMID: 35052616
Hybrids based on an aza-analogue of CGP37157, a mitochondrial Na/Ca exchanger antagonist, and lipoic acid were obtained in order to combine in a single molecule the antioxidant and NRF2 induction...
8.
Cores A, Carmona-Zafra N, Martin-Camara O, Sanchez J, Duarte P, Villacampa M, et al.
Antioxidants (Basel)
. 2022 Jan;
11(1).
PMID: 35052532
Curcumin shows a broad spectrum of activities of relevance in the treatment of Alzheimer's disease (AD); however, it is poorly absorbed and is also chemically and metabolically unstable, leading to...
9.
Gonzalez-Ruiz V, Cores A, Martin-Camara O, Orellana K, Cervera-Carrascon V, Michalska P, et al.
Pharmaceutics
. 2021 Oct;
13(10).
PMID: 34683902
The use of cyclodextrins as drug nano-carrier systems for drug delivery is gaining importance in the pharmaceutical industry due to the interesting pharmacokinetic properties of the resulting inclusion complexes. In...
10.
Martin-Camara O, Cores A, Lopez-Alvarado P, Menendez J
Eur J Med Chem
. 2021 Aug;
225:113742.
PMID: 34388381
Synaptic spine morphology is controlled by the activity of Rac1, Cdc42 and RhoA, which need to be finely balanced, and in particular RhoA/ROCK prevents the formation of new protrusions by...