» Authors » Andrew S Dixon

Andrew S Dixon

Explore the profile of Andrew S Dixon including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 15
Citations 900
Followers 0
Related Specialties
Top 10 Co-Authors
Published In
Affiliations
Soon will be listed here.
Recent Articles
11.
Dixon A, Miller G, Bruno B, Constance J, Woessner D, Fidler T, et al.
Mol Pharm . 2011 Dec; 9(1):187-95. PMID: 22136227
The oncoprotein Bcr-Abl drives aberrant downstream activity through trans-autophosphorylation of homo-oligomers in chronic myelogenous leukemia (CML).(1, 2) The formation of Bcr-Abl oligomers is achieved through the coiled-coil domain at the...
12.
Dixon A, Pendley S, Bruno B, Woessner D, Shimpi A, Cheatham 3rd T, et al.
J Biol Chem . 2011 Jun; 286(31):27751-60. PMID: 21659527
Oligomerization is an important regulatory mechanism for many proteins, including oncoproteins and other pathogenic proteins. The oncoprotein Bcr-Abl relies on oligomerization via its coiled coil domain for its kinase activity,...
13.
Mossalam M, Dixon A, Lim C
Ther Deliv . 2010 Nov; 1(1):169-93. PMID: 21113240
This article focuses on drug targeting to specific cellular organelles for therapeutic purposes. Drugs can be delivered to all major organelles of the cell (cytosol, endosome/lysosome, nucleus, nucleolus, mitochondria, endoplasmic...
14.
Dixon A, Lim C
Biotechniques . 2010 Jul; 49(1):519-24. PMID: 20615205
Protein interactions are critical for normal biological processes and molecular pathogenesis. While it is important to study these interactions, there are limited assays that are performed inside the cell, in...
15.
Dixon A, Kakar M, Schneider K, Constance J, Paullin B, Lim C
J Control Release . 2009 Jul; 140(3):245-9. PMID: 19576252
Altering the subcellular localization of signal transducing proteins is a novel approach for therapeutic intervention. Mislocalization of tumor suppressors, oncogenes, or factors involved in apoptosis results in aberrant functioning of...