Andrew Morrell
Overview
Explore the profile of Andrew Morrell including associated specialties, affiliations and a list of published articles.
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Articles
24
Citations
427
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0
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Recent Articles
1.
Beal D, Liang M, Brown I, Budge J, Burrows E, Howland K, et al.
Mater Adv
. 2023 Jul;
4(14):2963-2970.
PMID: 37465645
Bacterial microcompartments (BMCs) are proteinaceous organelle-like structures formed within bacteria, often encapsulating enzymes and cellular processes, in particular, allowing toxic intermediates to be shielded from the general cellular environment. Outside...
2.
Okonkwo A, Blizzard R, Anand S, Morrell A, Bardan A, Dunleavy D
Eye (Lond)
. 2022 Dec;
37(11):2169-2171.
PMID: 36517578
No abstract available.
3.
Prajapati R, Salada A, Okonkwo A, Sarfraz N, Bardan A, Dunleavy D, et al.
Eye (Lond)
. 2022 Oct;
37(4):790-791.
PMID: 36261493
No abstract available.
4.
Conda-Sheridan M, Reddy P, Morrell A, Cobb B, Marchand C, Agama K, et al.
J Med Chem
. 2012 Dec;
56(1):182-200.
PMID: 23259865
Tyrosyl-DNA phosphodiesterase I (Tdp1) plays a key role in the repair of damaged DNA resulting from the topoisomerase I (Top1) inhibitor camptothecin and a variety of other DNA-damaging anticancer agents....
5.
Nguyen T, Morrell A, Conda-Sheridan M, Marchand C, Agama K, Bermingham A, et al.
J Med Chem
. 2012 Aug;
55(16):7297.
PMID: 22891611
No abstract available.
6.
Chen L, Conda-Sheridan M, Reddy P, Morrell A, Park E, Kondratyuk T, et al.
J Med Chem
. 2012 Jun;
55(12):5965-81.
PMID: 22712432
Activation of the retinoid X receptor (RXR), which is involved in cell proliferation, differentiation, and apoptosis, is a strategy for cancer chemotherapy and chemoprevention, and 3-amino-6-(3'-aminopropyl)-5H-indeno[1,2-c]isoquinoline-5,11-(6H)dione (AM6-36) (3) is among...
7.
Nguyen T, Morrell A, Conda-Sheridan M, Marchand C, Agama K, Bermingham A, et al.
J Med Chem
. 2012 Apr;
55(9):4457-78.
PMID: 22536944
Substances with dual tyrosyl-DNA phosphodiesterase I-topoisomerase I inhibitory activity in one low molecular weight compound would constitute a unique class of anticancer agents that could potentially have significant advantages over...
8.
Musa F, Patil S, Rafiq O, Galloway P, Ball J, Morrell A
Clin Exp Ophthalmol
. 2012 Mar;
40(8):780-5.
PMID: 22429901
Background: To determine the prevalence and severity of intraocular pressure changes after deep anterior lamellar keratoplasty and its effect on visual function. Design: Retrospective cohort study. Participants: All patients undergoing...
9.
Kiselev E, DeGuire S, Morrell A, Agama K, Dexheimer T, Pommier Y, et al.
J Med Chem
. 2011 Aug;
54(17):6106-16.
PMID: 21823606
A series of 7-azaindenoisoquinoline topoisomerase I (Top1) inhibitors have been prepared to investigate the effect of increased electron affinity of the aromatic system on the ability to stabilize the Top1-DNA...
10.
Park E, Kondratyuk T, Morrell A, Kiselev E, Conda-Sheridan M, Cushman M, et al.
Cancer Prev Res (Phila)
. 2011 Apr;
4(4):592-607.
PMID: 21464033
Retinoid X receptor (RXR) has been targeted for the chemoprevention and treatment of cancer. To discover potential agents acting through RXRs, we utilized an RXR response element (RXRE)-luciferase reporter gene...